Protein Alignment ppk25 and ASIC3

DIOPT Version :9

• Sequence 1: NP_995766.1
• Gene: ppk25 / 2768722
• FlyBaseID: FBgn0053349
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_064717.1
• Gene: ASIC3 / 9311
• HGNCID: 101
• Length: 549
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 96/526 - (18%)
• Similarity: 163/526 - (30%)
• Gaps: 193/526 - (36%)

  Fly    22 SIHGMPYI-------ARRDLHWAERLFWTFIILGSA--YYAISSCLNQWYRFRDNPIVYEYEYLF 77
            |:||:.::       .||.: ||     ..::|..|  .|.::..:..:..|.....:.|.|  .
Human    25 SMHGLGHVFGPGSLSLRRGM-WA-----AAVVLSVATFLYQVAERVRYYREFHHQTALDERE--S 81

  Fly    78 GLRIFPFVGITLCPRYHDETEIPRLINQT-----------W------GVDPSEDKEKAVYYRKFL 125
            ...|||  .:|||.           ||..           |      |:||:|       :..||
Human    82 HRLIFP--AVTLCN-----------INPLRRSRLTPNDLHWAGSALLGLDPAE-------HAAFL 126

  Fly   126 LAINGLRYSTLETLEP-----FENDTTLDNVN-YLNILLTLQKKVIAVKI------PPELAPIIT 178
            .|:.          .|     |....|.|... |.....:|...::..:.      |.....|.|
Human   127 RALG----------RPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFT 181

  Fly   179 EVGLCQTSSQ---------LNRYGNPYG---KLETQDMEPMKQCGYLSNCITSLKPI------NS 225
            .:|.|.|.:.         ..|.|...|   .|:.|..|      ||        |:      ..
Human   182 RMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEE------YL--------PVWRDNEETP 232

  Fly   226 IVAPIFMYLHDVEEMMLPDDMR---TPSFDAKDIESKDLDIMLHTTSAESEVRNLPVAYRKCRFS 287
            ....|.:.:|..||..:.|.:.   :|.:..            ..:..:.::..||..:..|. |
Human   233 FEVGIRVQIHSQEEPPIIDQLGLGVSPGYQT------------FVSCQQQQLSFLPPPWGDCS-S 284

  Fly   288 DENNLQY---------------YSPYHPSLCRLECRIKWALSLCNCKPYFYVAAPEVPICT---- 333
            ...|..|               ..||....|||.|..::....|.|:..:...  :||:|:
Human   285 ASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPG--DVPVCSPQQY 347

  Fly   334 -------VSGMLCLARSKWLERPCDCYPSCREETF----TIFKVSDQTGGDDNYSGERF------ 381
                   :..||       .:..|.|...|....:    ::.::..:       :..||
Human   348 KNCAHPAIDAML-------RKDSCACPNPCASTRYAKELSMVRIPSR-------AAARFLARKLN 398

  Fly   382 -------ERTLIINLQISRMG---INRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGVVYFFLTF 436
                   |..|.:::....:.   :.::..:...:|:...||.:|||:|||.:||       |..
Human   399 RSEAYIAENVLALDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTI-------LEI 456

  Fly   437 IAYTCK 442
            :.|.|:
Human   457 LDYLCE 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	93/514 (18%)
ASIC3	NP_064717.1	ASC	20..534	CDD:295594	96/526 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..307		2/21 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920