DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk25 and asic1a

DIOPT Version :9

Sequence 1:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_021333995.1	Gene:	asic1a / 791696	ZFINID:	ZDB-GENE-040513-2	Length:	614	Species:	Danio rerio

Alignment Length:	497	Identity:	104/497 - (20%)
Similarity:	188/497 - (37%)	Gaps:	104/497 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QPDWLAELCQESSIHGMPYIARRDLHWAERLFWTFIILGSAYYAISSCLNQWYRFRDNPIVYEY- 73
            ||..|......|::||:.:|...:...|:...|....|.|..:.:..|:::...:.:.|.|.:.
Zfish   132 QPPPLQVFAHTSTLHGISHIFSYEKITAKCCLWVVFFLSSLTFLMYVCIDRIQFYLEYPHVTKLD 196

  Fly    74 EYLFGLRIFPFVGITLC-------------PRYHDETEIPRLINQTWGVDPSEDKEKAVYYRKFL 125
            |....:.:||  .:|:|             ..|| ..|:..|:|....|..:...|::|
Zfish   197 EITTPVMVFP--AVTICNLNSIRFSRITRNDLYH-AGELLALLNSRHEVREAHLVEESV------ 252

  Fly   126 LAINGLRYST-LETLEP-------FENDTTLDNVNYLNILLTLQKKVIAVKIPPELAPIITEVGL 182
              :..|:..| ..:.:|       |.|.|..|   ..::||:.|.:....: |.:.:.:.|..|.
Zfish   253 --MEVLKSKTDFRSFKPRHFNMWEFYNRTGHD---IKDMLLSCQFRGSPCR-PEDFSVVFTRYGK 311

  Fly   183 CQTSSQLNRYGNPYGKLE------TQDMEPMKQCGYLSNCITSLKPI------NSIVAPIFMYLH 235
            |.|.:. ...|.|...::      .:.|..::|..||        |:      :|..|.|.:.:|
Zfish   312 CYTFNS-GETGPPRVSVKGGMGNGLEIMLDIQQDEYL--------PVWGESDESSFEAGIKVQIH 367

  Fly   236 DVEEMMLPDDMR---TPSFDAKDIESKDLDIMLHTTSAESEVRNLPVAYRKCRFSDENNLQYYSP 297
            ..:|....|.:.   .|.|..            ..:..|..:..||..:..|: |...:..|:..
Zfish   368 SQDEPPFIDQLGFGVAPGFQT------------FVSCQEQRLVYLPAPWGSCK-STPPSSDYFRA 419

  Fly   298 YHPSLCRLECRIKWALSLCNCKPYFYVAAP-EVPICT----------VSGMLCLARSKW--LERP 349
            |..|.||.:|..::.:..|||:   .|..| :.|.||          ....|....|.:  .|.|
Zfish   420 YSISACRTDCETRYLVENCNCR---MVHMPGDAPYCTPVLYKECAHPALDFLVETDSDYCSCETP 481

  Fly   350 CDCYPSCREETFTIFKVSDQTGGD---DNYS-GERF--ERTLIINLQISRMG---INRRVVFSTD 405
            |:.....:|.:|.  |:..:....   ..|| .|::  |..:::::....:.   |.:|..:...
Zfish   482 CNITRYSKELSFV--KIPSKASVKYLAKKYSKSEKYITENVMVLDVFFEALNYETIEQRKAYEVA 544

  Fly   406 QLIMSFGGAIGLFLGASFMTI---YGVVYFFLTFIAYTCKNR 444
            .|:...||.:|||:|||.:||   :..:|..:.:....|.|:
Zfish   545 GLLGDIGGQMGLFIGASILTILELFDYLYEVMKYRLCRCSNK 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	98/475 (21%)
asic1a	XP_021333995.1	ASC	136..582	CDD:322155	100/487 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020