Protein Alignment ppk25 and asic1c

DIOPT Version :10

• Sequence 1: NP_995766.1
• Gene: ppk25 / 2768722
• FlyBaseID: FBgn0053349
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_021325802.1
• Gene: asic1c / 407670
• ZFINID: ZDB-GENE-040513-3
• Length: 562
• Species: Danio rerio
• Alignment Length: 490
• Identity: 105/490 - (21%)
• Similarity: 175/490 - (35%)
• Gaps: 144/490 - (29%)

  Fly    21 SSIHGMPYIARRDLHWAERLFWTFIILGSAYYAISSCLNQWYRFRDNPIVYEYEYLFGLRIF--- 82
            :.:||:.:.........:||||...:|        .||...:.:..|.|:|...|....:|:
Zfish    45 TKVHGLKHAFSPHKSKTQRLFWLLALL--------VCLGLLFTWSWNRILYLLSYPAVTKIYMVW 101

  Fly    83 ----PFVGITLCPR------------------YHDETEIPRLINQTWGVDPSEDKEKAVYYRKFL 125
                .|..||.|.:                  :.|...:...:|:     .|....|...:|:.|
Zfish   102 SNNMTFPAITFCNQNRLRVSSLTRDDLYYSGYWMDILHLNHTLNR-----QSVSMLKHSRHRERL 161

  Fly   126 L-AINGLRYS-----TLETLEPFE------NDTTL------DNVNYLNILLTLQKKVIAVKIPPE 172
            | .::...||     :|.|.|..:      .|..|      :|..|.|
Zfish   162 LHLLDFSHYSPPPDQSLNTTEMIDRLGHQLQDMLLECRFRGENCTYKN----------------- 209

  Fly   173 LAPIITEVGLCQT-SSQLNRYGNPYGKLET---------QDMEPMKQCGYLSNCITSLKPI---- 223
            ..||.|..|.|.| :|.|:  |||.  |.|         :.|..::|..||        |:
Zfish   210 FTPIYTRYGKCYTFNSGLD--GNPL--LTTLKGGTGNGLEIMLDIQQDEYL--------PVWGDT 262

  Fly   224 --NSIVAPIFMYLHDVEEMMLPDDMR---TPSFDAKDIESKDLDIMLHTTSAESEVRNLPVAYRK 283
              .|..|.|.:.:|..:|....|.:.   .|.|  :...|....::|:          ||..:..
Zfish   263 DETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGF--QTFVSCQQQLLLY----------LPPPWGD 315

  Fly   284 CRFSDENNLQYYSPYHPSLCRLECRIKWALSLCNCKPYFYVAAPEV-PICTVSGML-CL--ARSK 344
            || |...:.:|:|.|..:.||::|..::.|..|||:   .|..|.. .:||..... |.  |...
Zfish   316 CR-SAPMDSEYFSTYSITACRIDCETRYLLENCNCR---MVHMPGTSTVCTPEQYKDCADPALDF 376

  Fly   345 WLERP---CDCYPSCREETF----TIFKVSDQTGGDDNYSGERFERT--------LIINLQISRM 394
            .:|:.   |.|...|....:    ::.|:..:...  .|..::|.:|        |::::....:
Zfish   377 LVEKDNDYCVCDTPCNMTRYGKELSMVKIPSKASA--KYLAKKFNKTEQYITDNILVLDIFFEAL 439

  Fly   395 G---INRRVVFSTDQLIMSFGGAIGLFLGASFMTI 426
            .   |.::..:....|:...||.:|||:|||.:||
Zfish   440 NYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:459966	105/490 (21%)
asic1c	XP_021325802.1	ENaC	34..531	CDD:273304	105/490 (21%)