Protein Alignment ppk25 and asic2

DIOPT Version :10

• Sequence 1: NP_995766.1
• Gene: ppk25 / 2768722
• FlyBaseID: FBgn0053349
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 510
• Identity: 105/510 - (20%)
• Similarity: 178/510 - (34%)
• Gaps: 150/510 - (29%)

  Fly     6 SRPKQP-DWLAE----LCQESSIHGMPYIARRDLHWAERLFWTFIILGSAYYAISSCLNQWYRFR 65
            :||..| |.|:.    |...:.:||:.:|.......:.|.||..        |..:||.....:.
Zfish    51 TRPGTPRDDLSRLTVALLSRTRLHGLRHICSPSNSLSRRAFWMI--------AFCTCLGLLLSWS 107

  Fly    66 DNPIVYEYEYLFGLRI-------FPFVGITLCPRYHDETEIPRLINQTWGVDPSEDKEKAVYYRK 123
            .|.:::...:....|:       ..|..:|:|     .....||.:.|     ..|...|.::..
Zfish   108 SNRLLHWLAFPTHTRVHTEWAKELAFPTVTIC-----NNNPVRLYHLT-----KSDLYFAGHWLG 162

  Fly   124 FLLAINGLRYSTLETLEP--------------------FENDTTLDNVNYLNILLTLQKKVIAVK 168
            .|||....|...|:.|:.                    ||. |:|:.::.|.  ..|:..::|.|
Zfish   163 LLLANRTARPLVLDLLQDDRRGWFSKLSDFRLFLPPRRFEG-TSLEFMDRLG--HQLEDMLLACK 224

  Fly   169 IPPELAPIITEVGLCQTSSQLNRYGNPY-------GK-LET----------QDMEPMKQCGYLSN 215
            ...|      ..|....|:...|||..|       || |.|          :.|..::|..||
Zfish   225 YRGE------PCGAHNFSTVFTRYGKCYMFNAAEEGKTLRTTMKGGTGNGLEIMLDIQQDEYL-- 281

  Fly   216 CITSLKPI------NSIVAPIFMYLHDVEEMMLPDDMR---TPSFDAKDIESKDLDIMLHTTSAE 271
                  |:      .:..|.:.:.:|...|.....::.   .|.|..            ...:.|
Zfish   282 ------PVWGETEETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQT------------FVATQE 328

  Fly   272 SEVRNLPVAYRKC--RFSDENNLQYYSPYHPSLCRLECRIKWALSLCNCKPYFYVAAPEVPICT- 333
            ..:..||..:.:|  |..|....|.||   .|.||:||..::.:..|||:..:...  :.|.||
Zfish   329 QRLTYLPPPWGECVSRALDSGLFQVYS---VSACRIECETRYIVENCNCRMVYMPG--DSPYCTP 388

  Fly   334 ----------------VSGMLCLARSKWLERPCDCYPSCREETFTIFKVSDQTGGDDNYSGERFE 382
                            |.|..|:.||     ||:.....:|  .::.|:..:|..  .|..::|.
Zfish   389 EQYKDCAEPALAALSAVEGTNCICRS-----PCNMTRYNKE--LSMVKIPSKTSA--RYLEKKFN 444

  Fly   383 RT--------LIINLQISRMG---INRRVVFSTDQLIMSFGGAIGLFLGASFMTI 426
            |:        |::::....:.   |.::..:....|:...||.:|||:|||.:|:
Zfish   445 RSEKYITDNILVLDVFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:459966	99/493 (20%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	99/490 (20%)