DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk25 and ppk18

DIOPT Version :9

Sequence 1:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_609308.3	Gene:	ppk18 / 34295	FlyBaseID:	FBgn0265001	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	110/558 - (19%)
Similarity:	186/558 - (33%)	Gaps:	184/558 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ELCQESSIHGM-PYIARRDLHWAERLFWTFI---------------------------------I 46
            |..::|.|:|: |::....:.:|:.::..|:                                 :
  Fly    15 EFLRQSYINGLHPFLYHTPVRYAKAIWLAFLTAIMIYTHIVIADLILEYLVQPTEIHMAPDLVHV 79

  Fly    47 LGSAYYAISSCLNQWYRFRDNPIVYEY-EYLF------------------GLRIFPFVGITLCPR 92
            ..|.:.|:..|.:.....|   ::..| |.||                  ..|:.......|.|.
  Fly    80 ANSPFPAVGVCTSNKINGR---LLRSYAEKLFHHQGNSSLQAVALDLDDMANRLLVLAQFYLNPL 141

  Fly    93 YHDE-----TEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGLRYST---LETLEPFENDTTLD 149
            ..|.     ||:.||                  :|..:...||..||.   |..|.|...|..:.
  Fly   142 ESDHERWNATELDRL------------------HRLLVAYHNGAGYSVRDILRDLSPGCGDLVIR 188

  Fly   150 NVNYLNILLTLQKKVIAVKIPPELAPIITEVGLCQTSSQLNRYGNP-YGKL------ETQDMEPM 207
            .:.:   .|.:....:.:|.|       |...:|    .:..|..| |.:.      |..:|..:
  Fly   189 GIVF---GLPVNASQLFLKRP-------TSSNVC----CIFNYRRPSYSQFLTKRAEEDSEMRAV 239

  Fly   208 KQCGYLSNCITSLKPINSIVAPIFMYLHDVEEMMLPDDMRT---------PSFDAKDIESKDLDI 263
            ....:.||.|     :||:.    ..|.|..:..:.:...:         |..|...|:|..|..
  Fly   240 PMVVFESNSI-----LNSVQ----FVLQDTPKEDITNTFHSNSAFQLIIFPQEDYATIQSTTLGE 295

  Fly   264 ML--HTT-----------SAESEVRNLPVAYRKCRFSDEN----NLQYYSPYHPSLCRLECRIKW 311
            :|  |.:           |:...||.:|...|:|.:.:|.    |..|||   ...|.|.||:|.
  Fly   296 VLVDHYSIVEIPIQPMFFSSGDGVRGVPPHIRRCYYPEEGMRLLNQSYYS---LDECLLVCRMKS 357

  Fly   312 ALSLCNC-KPYFYVAAPEVPICTVSGMLCLARSK--W----------------LERPCD-CYPSC 356
            .:..|.| .|....::.::..|.:..:.||.|.|  |                ::|.|: |.|:|
  Fly   358 MIDHCGCVSPPLTGSSMDLDYCMLPDLPCLMRWKSIWYGYSDFAYLQNKEENLVQRQCEHCLPTC 422

  Fly   357 REETFTI-FKVSD--QTGGDDNY-----SGERFERTLII-----NLQISRMGINRRVVFSTDQLI 408
            ...:.:| ..|:.  :|.....|     .|...||.|.|     .|:.:: ....::|.|...|:
  Fly   423 NGVSMSITTNVAPLRRTYNSSGYFTGLLKGLTNERPLAIIKLFFKLRFAQ-ATKSQMVSSWVVLL 486

  Fly   409 MSFGGAIGLFLGAS---------FMTIYGVVYFFLTFI 437
            ..|||.:.|..|.|         ::|..|.||.:.:|:
  Fly   487 NRFGGILSLMYGFSIVSYIEILYYLTGKGFVYIYRSFL 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	107/549 (19%)
ppk18	NP_609308.3	ASC	16..510	CDD:279230	104/541 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020