DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk25 and ppk13

DIOPT Version :9

Sequence 1:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	113/483 - (23%)
Similarity:	194/483 - (40%)	Gaps:	104/483 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LAELCQESSIHGMPYIARRDLHWAERLFWTFIILGSAYYA---ISSCLNQWYRFRDNPIVYEYEY 75
            :.|..:.|::||..:|..:|..|.||:||...::.|.|.:   |.:.|:   .|.:|.|.:..|.
  Fly     7 IEEYLKNSTLHGARFIVDKDASWIERIFWVICLVASWYASWLLIKASLS---AFENNAISFVVES 68

  Fly    76 LFGLRIFPFVGITLCPRYHDETEIPRLINQTWGVD--------------------------PSED 114
            .|......|..|.:|...:.: .|..:..|.||.|                          ..|:
  Fly    69 SFRDWNTNFPAIIVCESKNMD-RIQEVAEQLWGADHDFTLEEVLSEIAFFRGESYHTVHECSGEE 132

  Fly   115 KEKAVYYRKFLLAINGLRYSTLETLEPFE-NDTTLDNVNYLNILLTLQKKVIAVKIPPELAPIIT 178
            ...:.:|..|......:|.|.::::...| |:...:...|.:                   .:.|
  Fly   133 VTASCFYSNFSYYAELVRSSCVDSISNCEWNNKPFECCKYFH-------------------RMET 178

  Fly   179 EVGLCQTSSQLNRYGNPYGKLETQDMEPMKQCGYLSNCITSLKPINSIVAPIFMYLHDVEEMMLP 243
            |:|:|...:.: :.|.|  |:...:|...:..|     ..:||......|.:|:.  ..||:
  Fly   179 ELGICYAINSM-QAGKP--KMPKLNMYSNRGSG-----PGALKMELHTEATVFIL--GTEEV--- 230

  Fly   244 DDMRTPSFD----------AKDIESKDLDIMLHTTSAESEVRNLPVAYRKCRFSDENNLQYYSPY 298
            ..:.||..|          .:.|..:|::       .:.|:|...|..|.|||:|||.|..:..|
  Fly   231 PTLVTPKTDFLVVGPYISFVRYISKRDIE-------NDEEIRQTSVHQRNCRFADENILDVHKFY 288

  Fly   299 HPSLCRLECRIKWALSLCNCKPYFYVAAPEVPICTVSGMLCLAR---------SKWLE------R 348
            ..|.|.::||....:.||||..:....:|:..:|.:.|:.||.|         :||.:      .
  Fly   289 SYSACTVQCRKDRQMELCNCSSHLSPNSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGRKGL 353

  Fly   349 PCDCYPSCRE-ETFTIFKVSDQTGGDDNYSGERFERTLIINLQISRMGINRRVVFSTDQLIMSFG 412
            .|||.|||.| :..|::...:...|..| :..|.|..||   ::......|.:|.....|::|.|
  Fly   354 VCDCLPSCTEVDITTVYDSKENMAGSQN-AISRIEVGLI---ELPTERYKRNLVRGKLDLVVSIG 414

  Fly   413 GAIGLFLGASFMTIYGVVYFFLTFIAYT 440
            |..|||:|||.:: :..:::::|...||
  Fly   415 GTTGLFVGASLLS-FVEIFYYITIRPYT 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	109/469 (23%)
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	109/471 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I7319
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920