DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk25 and del-10

DIOPT Version :9

Sequence 1:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	77/366 - (21%)
Similarity:	121/366 - (33%)	Gaps:	113/366 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 PSEDKEKAVYYRKFLL-----AINGLRYSTLETLEPFENDTTLDNVNYLNILLTLQKKVIAVKIP 170
            |...:||......|||     ..|..||.::..|:....|...|....:.::|.:.:|:..|.:|
Worm   561 PITSEEKKANQMFFLLDETAFNRNATRYMSVGDLKSRYGDKVDDVAEEIAVILRIMEKLWHVFMP 625

  Fly   171 PELAPIITEVGLCQTSSQLNRYGNPYGKLETQDMEPMKQCGYLSNCITSLKPINSIVAPIFMY-L 234
                                   :.|.:..|.|...|.:...|.|                .| |
Worm   626 -----------------------DSYIRTMTGDFSRMDRIIELMN----------------QYEL 651

  Fly   235 HDVEEMMLPDDMRTPS----FDAKDIES------KDLDIMLHTTSAESEVRNLPVAYRKCR---- 285
            :.::.....:.|::..    |:....||      ||||..|.....|.|.....|.|...|
Worm   652 NKLQRRAWAEKMQSRQMKHFFEDDFYESYYQPLIKDLDTTLVKQIDEVEADWPKVEYYLQRGSAG 716

  Fly   286 -------FSDEN--NLQYYSPYHPSLCRLECRIKWALSLCNCKPYFYVAAPEVPICTVSGMLCLA 341
                   |.|.|  |.|.:.             |..:.:..|               .||.:...
Worm   717 KTGAIMFFGDGNKDNRQKFE-------------KLIVEMHEC---------------ASGKMRKE 753

  Fly   342 RSKWLERPCDCYPSCREETFTIFK--VSDQTGGDDNYS-GERF--ERTLIINLQISRMGINRRVV 401
            ..|.|......|...:.....:||  :.|..   :|:. |.:|  :...::|:.:.||.:.   |
Worm   754 AGKMLSSFKKSYRELQAAYGKLFKEELPDYL---ENFQFGNKFVGDNFAMVNIFLHRMNLE---V 812

  Fly   402 FSTDQ------LIMSFGGAIGLFLGASFMTIYGVVYFFLTF 436
            :|.|:      |....|||:|||||||.:||..:||..:.:
Worm   813 WSQDRTYGFWSLACDIGGALGLFLGASLLTIIEIVYLCIQY 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	76/360 (21%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230
del-10	NP_495302.3	ASC	<789..849	CDD:279230	22/62 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820