DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk25 and scnn1g

DIOPT Version :9

Sequence 1:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	XP_031749443.1	Gene:	scnn1g / 100487822	XenbaseID:	XB-GENE-980897	Length:	672	Species:	Xenopus tropicalis

Alignment Length:	595	Identity:	113/595 - (18%)
Similarity:	184/595 - (30%)	Gaps:	230/595 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PKQPDWLAEL----CQESSIHGMPYIA------RRDLHW-------AERLFWTFIILGSAYYAIS 55
            |:.|. |.||    |..::.||...|.      ||.: |       ...:||...:|..:||::|
Frog    31 PQAPT-LYELMQWYCLNTNTHGCRRIVVSKGRLRRWI-WIVLTLCAVALIFWQCALLLMSYYSVS 93

  Fly    56 SCLNQWYRFRDNPIVYEYEYLFGLRIFPFVGITLCPRYHDETEIPRLINQTWGVDPSEDKEKAVY 120
            :.:.               ..|...:||  .:|:|                 .::|..
Frog    94 ASIT---------------VTFQKLVFP--AVTIC-----------------NLNPYS------- 117

  Fly   121 YRKFLLAINGLRYSTLETL-------EPF----------ENDT----------TLDNV--NYLNI 156
            |.|....::.|...|.:||       ||.          ||.|          .|::|  |.|.:
Frog   118 YSKIKDRLSALERETSQTLKNIYGFTEPLVRSKRDVEVDENSTDIFIKQIPLYRLESVQGNQLVV 182

  Fly   157 --LLTLQKKVIAVKIPPELAPIITEVG------LCQT-----------SSQLN--------RYGN 194
              |.|.::..::.|:....|..:.:.|      ||..           ||.:|        .|.|
Frog   183 SDLKTKKRTRMSAKVIHRDAESVQDPGNMVGFKLCDPNNSSDCTIFTFSSGVNAIQEWYRLHYTN 247

  Fly   195 PYGKLETQDMEPMKQCGY----------------------------LSNCIT------------- 218
            ...|:..:|...|   ||                            ..||.|
Frog   248 VLAKISMEDKIAM---GYKADELIVTCFFDGLSCDARNFTLFHHPLYGNCYTFNSAERGNLLVSS 309

  Fly   219 ------SLK-----------PINSIVAPIFMYLHDVEEMMLPDDMRTPSFDAKDIE-SKDLDIML 265
                  .||           |..|..|...:.:||.:|....:|:.|      ::| :.:..|.:
Frog   310 MGGAEYGLKVVLYIDEDEYNPYLSTAAGAKILVHDQDEYPFIEDLGT------ELETATETSIGM 368

  Fly   266 HTTSAESEVRNLPVAYRKCRFSDEN----NLQYYSPYHPSLCRLECRIKWALSLCNCKPY----- 321
            ..|    |...|...|..|.....:    || |...|...:|...|..:..:..|.|..|
Frog   369 QLT----ESTKLSDPYSDCTMDGSDVSVENL-YSKKYTLQICLNSCFQREMVRTCGCAHYDQPLP 428

  Fly   322 ---FYVAAPEVPICTVSGMLCLAR--SKWLERPCDCYPSCREE------TFTIFKVSDQTGGDDN 375
               .|....|.|    |.:.|..:  .::::....|..:|||.      |.|.......:...:.
Frog   429 NGAKYCNYEEYP----SWIYCYFKLYKQFVQEELGCQSACRESCSFKEWTLTRSLAKWPSLNSEQ 489

  Fly   376 YS--------GERFERTL----IINLQISRMGINRRVV-----FSTDQLIMSFGGAIGLFLGASF 423
            :.        ||:..:.|    :.||.|....:|.|.:     ::...|:.:|||.:||::..|.
Frog   490 WMLRVLSWELGEKLNKNLTKNDLANLNIFYQDLNSRSISESPTYNIVTLLSNFGGQLGLWMSCSM 554

  Fly   424 MTIYGVVYFF 433
            :.:..:|..|
Frog   555 ICVLEIVEVF 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:279230	107/578 (19%)
scnn1g	XP_031749443.1	ENaC	35..651	CDD:273304	111/591 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010