Protein Alignment ppk25 and asic4

DIOPT Version :10

• Sequence 1: NP_995766.1
• Gene: ppk25 / 2768722
• FlyBaseID: FBgn0053349
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_031749131.1
• Gene: asic4 / 100486325
• XenbaseID: XB-GENE-940165
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 480
• Identity: 108/480 - (22%)
• Similarity: 173/480 - (36%)
• Gaps: 111/480 - (23%)

  Fly    14 LAELCQESSIHGMPYIARRDLHWAERLFWTFIILGSA---YYAISSCLNQWYRFRDNPIVYEY-E 74
            ||.....|::||:.:|.:......::..|....|.|.   .|.::.|.   ..:.::|.|... |
 Frog    41 LAAFASTSTLHGLRHIFQTGRLGIKQSLWALAFLASLLFFLYQVAKCA---LYYLEHPHVTAVDE 102

  Fly    75 YLFGLRIFPFVGITLC--PRYH----DETEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGLRY 133
            .:.|..|||  .||:|  .|:.    .:.:|..|.|.| |: |.:|:|             |.|.
 Frog   103 EVMGEMIFP--AITICNINRFRHSALTDPDIYHLANLT-GL-PPKDRE-------------GHRD 150

  Fly   134 STLETLEPFENDTTLDNVNYLNILLTLQKKVIAVK----IPPELAPIITEVGLCQTSS------Q 188
            |.|    .:::...||.||.....|....|.....    .....:.:.|..|.|.|.:      :
 Frog   151 SDL----MYDDPDMLDIVNRTGHQLAEMLKSCNFSGDSCSAQNFSVVFTRYGKCYTFNADKKHPK 211

  Fly   189 LNRYGNPYGKLETQDMEPMKQCGYLSNCITSLKPI------NSIVAPIFMYLHDVEEMMLPDDMR 247
            ::|.|.....||.  |..::|..||        ||      .|..|.|.:.:|..:|......|.
 Frog   212 VSRQGGMGNGLEI--MLDIQQEEYL--------PIWRETNETSFEAGIRVQIHSQDEPPYIHQMG 266

  Fly   248 ---TPSFDAKDIESKDLDIMLHTTSAESEVRNLPVAYRKCRFS--DENNLQYYSPYHPSLCRLEC 307
               :|.|..            ..:..|..:..||..:..||.|  .|..|..||.|..|.|||:|
 Frog   267 FGVSPGFQT------------FVSCQEQRMTYLPQPWGNCRSSIPGEEFLSGYSTYSISACRLQC 319

  Fly   308 RIKWALSLCNCK------------PYFYVAAPEVPICTVSGMLCLARSKWLERPCDCYPSCREET 360
            ..:..:..|.|:            |..|:.|..:    :..|:.....|     |.|...|....
 Frog   320 EKEAVIRKCACRMVHMPGNETICSPVMYMCADHI----LDNMVEDTSEK-----CSCPTPCNLTR 375

  Fly   361 FT--IFKVSDQTGGDDNYSGERF--------ERTLIINLQISRMG---INRRVVFSTDQLIMSFG 412
            ::  |..|.....|...|...::        |..|::::....:.   |.::..:....|:...|
 Frog   376 YSKEISMVRIPNKGSARYLARKYNKNETYIRENFLVLDIFFEALNYETIEQKKAYDLPSLLGDIG 440

  Fly   413 GAIGLFLGASFMTIYGVVYFFLTFI 437
            |.:|||:||||:||..::.:....|
 Frog   441 GQMGLFIGASFLTILEILDYMYEVI 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk25	NP_995766.1	ASC	18..432	CDD:459966	105/469 (22%)
asic4	XP_031749131.1	ENaC	39..514	CDD:273304	108/480 (23%)