DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12d1-d and CYP72A14

DIOPT Version :9

Sequence 1:	NP_995812.1	Gene:	Cyp12d1-d / 2768720	FlyBaseID:	FBgn0053503	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_188086.1	Gene:	CYP72A14 / 820696	AraportID:	AT3G14680	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	112/486 - (23%)
Similarity:	192/486 - (39%)	Gaps:	106/486 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GEFQN--ASITEYTSAMRKRYGDI--YVMP--------------GMFGRKDWVTTFNTKDIEMVF 107
            |:|:.  :...|.||...|...||  .|||              ..||....:|..:.:.|:.||
plant    54 GDFKKMISMFIEATSKPIKPTDDITPRVMPHPLQMLKTHGRTNLTWFGPIPTITIMDPEQIKEVF 118

  Fly   108 RNEGIWPRRDGLDSIVY-FRE-HVRP--DVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMY 168
            ..             || |:: |..|  .:.|  .|||:...:.|.:.|..|||.|        :
plant   119 NK-------------VYDFQKAHTFPLSKILG--TGLVSYDGDKWAQHRRIINPAF--------H 160

  Fly   169 YEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALT 233
            .|.:.|:.:.|.|...|:            ..|..:||.:.......|...||        .::|
plant   161 LEKIKNMVHVFHESCSEL------------VGEWDKLVSDKGSSCEVDVWPGL--------TSMT 205

  Fly   234 LFQTSRDIFRLTFK-----LDIQPSMWKIIS-------TPTY--------RKMKRTLNDSLNVSQ 278
            ....||..|..:::     .::|..:.:::.       .|.|        |:||....:..::.:
plant   206 ADVISRTAFGSSYREGHRIFELQAELAQLVMQAFQKFFIPGYIYLPTKGNRRMKTAAREIQDILR 270

  Fly   279 KMLKENQDALEKRRQAGEKINSNSMLERLMEID--------PKVAVIMSLDILF--AGVDATATL 333
            .::.:.    |:.|::|| ..|..:|..|:|.:        .....:|....||  ||.:.|:.|
plant   271 GIINKR----ERARESGE-APSEDLLGILLESNLGQTEGNGMSTEDMMEECKLFYLAGQETTSVL 330

  Fly   334 LSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTC 398
            |...::.||:|.|.||:.|||:..:...|..  :.|.:..:..:..::.|.||.||......|..
plant   331 LVWTMVLLSQHQDWQARAREEVKQVFGDKQP--DTEGLNQLKVMTMILYEVLRLYPPVVQLTRAI 393

  Fly   399 QNDVILSGYRVPKGTTVLLGSNVLMKEATYYPR-PDEFLPERWLRDPETGKKMQVSPFTFLPFGF 462
            ..::.|....:|.|..:.|...::.::...:.. ..||.|||:........|.|||   |.||.:
plant   394 HKEMKLGDLTLPGGVQISLPVLLVHRDTELWGNDAGEFKPERFKDGLSKATKNQVS---FFPFAW 455

  Fly   463 GPRMCIGKRVVDLEMETTVAKLIRNFHVEFN 493
            |||:|||:....||.:..::.:::.|..|.:
plant   456 GPRICIGQNFTLLEAKMAMSLILQRFSFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	110/475 (23%)
CYP72A14	NP_188086.1	p450	24..512	CDD:299894	112/486 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010