DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp12d1-d and CYP71A12

DIOPT Version :9

Sequence 1:	NP_995812.1	Gene:	Cyp12d1-d / 2768720	FlyBaseID:	FBgn0053503	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_180633.3	Gene:	CYP71A12 / 817626	AraportID:	AT2G30750	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	115/512 - (22%)
Similarity:	200/512 - (39%)	Gaps:	121/512 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GEFQNASITEYTS--AMRKRYGDIYVMPGMFGRKDWVT---------TFNTKDIEMVFRNEGIWP 114
            |.....|:..:.|  ::..|||.:.::  .|||...:.         ...|.|::...|     |
plant    44 GNLHQLSLHPHRSLHSLSLRYGPLMLL--HFGRVPILVVSSGEAAQEVLKTHDLKFANR-----P 101

  Fly   115 RRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEF 179
            |...:..::.....|....|||.          |.:::|......:..:.:..:.:......||.
plant   102 RSKAVHGLMNGGRDVVFGPYGEY----------WRQMKSVCILNLLTNKMVASFEKIREEELNEM 156

  Fly   180 IERIKEIRDPKTLE--------VPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQ 236
            |:::::.....:.|        :|.|.|..|      :||           ||:.::..|..|.:
plant   157 IKKLEKASSSSSSENLSELFVTLPSDVTSRI------ALG-----------RKHSEDETARDLKK 204

  Fly   237 TSRDIFRLTFKL---DIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKE----NQDALEK---- 290
            ..|.|..|..:.   |..|::..|              |.:|.....:||    ..|.::|
plant   205 RVRQIMELLGEFPIGDYVPALAWI--------------DRINGFNARIKEVSQGFSDLMDKVVQE 255

  Fly   291 RRQAGEKINSNSMLERLMEIDPKVAV----------IMSLDILFAGVDATATLLSAVLLCLSKHP 345
            ..:||.  :....::.|:.|:.:.::          .|.||:...|...::|||..::..|.::|
plant   256 HLEAGN--HKEDFVDILLSIESEKSIGFQAQRDDIKFMILDMFIGGTSTSSTLLEWIMTELIRNP 318

  Fly   346 DKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPN-GFGTMRTCQNDVILSGYRV 409
            :...||::|:.|.:....|.:.|:::::|.||:|||||..|.:|. .....|....||.:.||.:
plant   319 NVMKKLQDEIRSTIRPHGSYIKEKDVENMKYLKAVIKEVFRVHPPLPLILPRLLSEDVKVKGYNI 383

  Fly   410 PKGTTVLLGSNVLMKE-ATYYPRPDEFLPERWLRD--PETGKKMQVSPFTFLPFGFGPRMCIGKR 471
            ..||.|::.:..:.:: |.:.|..:||.|||.|..  ...||.:     .|:|||.|.|:|.|..
plant   384 AAGTEVIINAWAIQRDPAIWGPDAEEFKPERHLDSTLDYHGKDL-----NFIPFGSGRRICPGIN 443

  Fly   472 VVDLEMETTVAKLIRNFH---------------VEFNRDASRPFKTMFLMEPAITFP 513
            :....:|.|||.|:..|.               ..|..|..|.|       |.|.||
plant   444 LALGLVEVTVANLVGRFDWRAEAGPNGDQPDLTEAFGLDVCRKF-------PLIAFP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	109/496 (22%)
CYP71A12	NP_180633.3	CYP71-like	63..489	CDD:410695	108/487 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000