Protein Alignment Cyp12d1-d and cyp27b1

DIOPT Version :10

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001298720.1
• Gene: cyp27b1 / 793309
• ZFINID: ZDB-GENE-111005-2
• Length: 505
• Species: Danio rerio
• Alignment Length: 502
• Identity: 136/502 - (27%)
• Similarity: 243/502 - (48%)
• Gaps: 51/502 - (10%)

  Fly    36 TEEHKTYDEIPRPNKFKFMR-AFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFN 99
            |.:.||.:::|.|:..:|:| .||..|   .:.:.:.....|::||.::  ...||....|....
Zfish    35 TPQVKTLEQMPGPSPARFIRDLFMKRG---FSRLHQLQLEGRQKYGPMW--KASFGPILTVHVAE 94

  Fly   100 TKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRG 164
            .:.|:.|.|.||..|.|..|.|...:|.     :.||..||:.::.|.|..:||.::...::|:.
Zfish    95 PELIQQVLRQEGQHPVRSELSSWKDYRA-----LRGEGYGLLTAEGEEWQCVRSLLSKHMLRPQA 154

  Fly   165 LRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNS 229
            :..|...|:.:.::.::::|......:..:..|.:.|..|...|.:..|.|:.::|.:
Zfish   155 VEAYDGALNAVVSDLLQKLKLRSQESSSRIVSDISAEFYRFGLEGISSVLFESRIGCL------- 212

  Fly   230 DALTLFQTSRDI------FRLTFKLDIQPSMW--KIISTP--TYRKMKRTLNDSL--NVSQKMLK 282
            ||:...:|.|.|      |.:|. |.:....|  :::..|  |:.:....:.:..  ::.|::.:
Zfish   213 DAVVPVETERFIQSINTMFVMTL-LTMAMPQWLHRLLPKPWDTFCRCWDVMFEFAKGHIDQRLQE 276

  Fly   283 ENQDALEKRRQAGEKINSNSMLERLMEID-PKVAVIMSL-DILFAGVDATATLLSAVLLCLSKHP 345
            |.|     :.:.||::....:...|.:.. |..:|..:: ::|.||||..::.||..|..||:||
Zfish   277 EKQ-----KLECGEQLEGRYLTYFLSQAGLPLTSVYSNVTELLLAGVDTISSTLSWSLYELSRHP 336

  Fly   346 DKQAKLREELLSIMPTKD-SLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRV 409
            |.|..||:|:||:|  || |:....::..||.|:||:||.||.||......|....|:.:.||.:
Zfish   337 DVQTALRDEVLSVM--KDRSVPQASDVAAMPLLKAVVKEILRLYPVIPANARVINKDIEVGGYVI 399

  Fly   410 PKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVS-PFTFLPFGFGPRMCIGKRVV 473
            ||.|.:.|......::...:..||.|.|:||      |.:...| |:..:|||.|.|.|||:|:.
Zfish   400 PKNTLITLCHYATSRDPQQFRDPDSFRPQRW------GDRSDRSHPYATVPFGVGKRSCIGRRIA 458

  Fly   474 DLEMETTVAKLIRNFHVEFNR--DASRPFKTMFLMEPAITFPFKFTD 518
            :||:...:::::.:|.:|..|  |...|. |..|:.|......:||:
Zfish   459 ELEVYLALSRILMHFTMEPVRENDTVHPM-TRTLLVPERQIDLRFTE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	124/456 (27%)
cyp27b1	NP_001298720.1	CYP27B1	72..500	CDD:410741	124/456 (27%)