Protein Alignment Cyp12d1-d and cyp46a1.2

DIOPT Version :9

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001072550.1
• Gene: cyp46a1.2 / 780005
• XenbaseID: XB-GENE-5802444
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 496
• Identity: 127/496 - (25%)
• Similarity: 225/496 - (45%)
• Gaps: 82/496 - (16%)

  Fly    39 HKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNT--- 100
            |..||.||.|.:..|              |..:::|:.|...:..:|...|  .|||..:..
 Frog    33 HMKYDHIPGPPRDSF--------------IFGHSTALLKLVNENLLMYDYF--LDWVHKYGPVMR 81

  Fly   101 -----KDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEV-------QGLVASQN-EAWGKLR 152
                 |...:|...|||   ::.|.|..|.::... |.:|.:       :||:..:: :.|.|.|
 Frog    82 INGLHKVAVLVASPEGI---KEFLMSPKYLKDEFY-DFFGSLFGERLMGKGLLTDRDYDHWHKQR 142

  Fly   153 SAINPIFMQP--RGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAF 215
            ..::|.|.:.  .||   ..|.:....|.:|::.|..|.| .||  :..|..|::..:.:|.|.|
 Frog   143 RIMDPAFSRTYLMGL---MGPFNEKAEELMEKLSENSDRK-CEV--NMHDMFSKVTLDVIGKVGF 201

  Fly   216 DRQMGLIRKNRDNSD---ALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVS 277
            ..::..:  |.|.:.   |::|....        .::|:..|.|      |...||.|...:..|
 Frog   202 GMELNSL--NDDQTPFPRAISLVMKG--------SVEIRNPMIK------YSLAKRGLIRKVQES 250

  Fly   278 QKMLKE-NQDALEKRR---QAGEKINSNSMLERL------MEIDPKVAVIMSLDILFAGVDATAT 332
            .::|:: .::.:|:|:   |.||:|..:.:.:.|      .:.||:..:...:....||.:.||.
 Frog   251 IRLLRQTGKECIERRQKQIQDGEEIPVDILTQILRGTALEKDCDPETLLDNFVTFFIAGQETTAN 315

  Fly   333 LLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRT 397
            .||..::.|.::|:...|.:.|:..::.:|.. :..|::..:.||..|:|||||.||...||.||
 Frog   316 QLSFAVMSLGRNPEILKKAQAEIDEVIGSKRD-IEYEDLGKLSYLSQVLKETLRLYPTAPGTSRT 379

  Fly   398 CQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGF 462
            .:|::::...|:|...|::|.|.|:.:...||..|..|.|:|:  .|:..|..    ||:.||..
 Frog   380 LENEIVIDEVRIPGNVTLMLNSYVMGRMEQYYKDPLMFNPDRF--SPDAPKPY----FTYFPFSL 438

  Fly   463 GPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTM 503
            |||.|||:....:|.:..:||.::.:  ||.....:.||.:
 Frog   439 GPRNCIGQVFSQMEAKVVMAKFLQRY--EFELAEGQSFKIL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	119/465 (26%)
cyp46a1.2	NP_001072550.1	p450	40..482	CDD:365848	123/489 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010