Protein Alignment Cyp12d1-d and cyp27a1.3

DIOPT Version :9

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_002934001.3
• Gene: cyp27a1.3 / 594905
• XenbaseID: XB-GENE-18386061
• Length: 518
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 131/495 - (26%)
• Similarity: 236/495 - (47%)
• Gaps: 57/495 - (11%)

  Fly    40 KTYDEIPRPNKFKFMR-AFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKD- 102
            ||.|::|.|:..|.:. .|:.|..|:.   .|.....:|.||.::.|.   .|:..:.|..:.|
 Frog    45 KTLDDLPGPSPLKLLYWIFLRGYLFRT---HELQVIFKKTYGPMWKMS---DRQHAMVTVASPDL 103

  Fly   103 IEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRM 167
            :|.:.|.||.:|.|  .|..: .|||  .|:.|...|.|..:...|.::|:.:|...::||...:
 Frog   104 LESLLRKEGKYPTR--ADMFI-MREH--RDLRGHSYGPVTEEGHQWHRIRTILNQRMLKPRETVV 163

  Fly   168 YYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEIS-RLVFESLGLVAFDRQMGLIRKNRDNSDA 231
            |...::.:.::.:.:|||:....:.....:...|:. :..|||:..|.|:.::|.:.|.
 Frog   164 YAGSMNEVVSDLLLKIKELTAQSSSGTQVNGVAELMYKFAFESICTVLFETRLGCLNKE------ 222

  Fly   232 LTLFQTSRDIFRLTFKLD-----IQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKR 291
             .|.:|.:.|..:...|:     .:...|.....|.:.:.....:...:..:|::.:..:.:|.|
 Frog   223 -ILPETQKFIDSIGIMLEHLTMLTRLPQWTKGILPYWGRYIEAWDTIFDFGKKLIDKKMEDIEGR 286

  Fly   292 RQAGEKINSNSMLERLM-------EIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQA 349
            .:.||::....:...|.       |:...|     :::|.||||.|:..|:..|..||::|:.|.
 Frog   287 LKRGEEVEGEYLTYLLSSGKLSMEEVYGSV-----VELLQAGVDTTSNTLTWALYQLSRNPEIQN 346

  Fly   350 KLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTC-QNDVILSGYRVPKGT 413
            .|.:|::.::| .:::.:.|.:..||.|:||||||||.:|......|.. :.:|.:..|..|..|
 Frog   347 NLYQEVIRVIP-GETIPDSEAIARMPLLKAVIKETLRLFPVVPENARMINEKEVTIKDYVFPVKT 410

  Fly   414 TVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEME 478
            ..:||...:.::.|.:|..|.|||||||||    ..|:..||..:|||:|.|.|:|:|:.:|||.
 Frog   411 QFILGHYAISRDETTFPEADRFLPERWLRD----SGMKHHPFGSIPFGYGVRACVGRRIAELEMH 471

  Fly   479 TTVAKLIRNFHVEFNRD-------------ASRPFKTMFL 505
            ..::::|:.|.|..:.|             |:||....|:
 Frog   472 LALSRIIKMFQVIPDPDLGEVGAKNRAVLVANRPVNLRFI 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	122/464 (26%)
cyp27a1.3	XP_002934001.3	cytochrome_P450	79..508	CDD:425388	120/453 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.060