Protein Alignment Cyp12d1-d and cyp27c1

DIOPT Version :10

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 124/464 - (26%)
• Similarity: 230/464 - (49%)
• Gaps: 31/464 - (6%)

  Fly    68 ITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKD-IEMVFRNEGIWPRRDGLDSIVYFREHVRP 131
            |.|......::||.|:  ...|| ..:|.:...|| :..|.|.|...|:|..::|...:||
 Frog    22 IQEIQQKHARQYGRIF--KSHFG-PQFVVSIADKDMVAQVLRAERDAPQRANMESWHEYRE---- 79

  Fly   132 DVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIR----DPKTL 192
             :.|...||::::.|.|..:||.:....::||.:.||...::.:..:.::||:::|    |..|:
 Frog    80 -LRGRSTGLISAEGEKWLNMRSVLRQKILRPRDVAMYSGGVNEVVEDLVKRIRKLRVQESDGLTV 143

  Fly   193 EVPEDFTDEISRLVFESLGLVAFDRQMGLI-----RKNRDNSDALTLFQTSRDIFRLTFKLDIQP 252
            ....|...:.|   .|::..:.::.::|.:     ::.::..:||.|..:   :|:.|......|
 Frog   144 TNVNDLYFKYS---MEAIATILYECRLGCLDDQIPQQTKEYIEALELMFS---MFKTTMYAGAIP 202

  Fly   253 SMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLM--EIDPKVA 315
            ...:.:....:|:..|:.:.....||..:.:....:|.:.:.||::....:...|:  |:|.:..
 Frog   203 KWLRPLIPKPWREFCRSWDGLFKFSQIHVDDRLRQIESQLEKGEEVQGGVLTHLLLSKELDLEEI 267

  Fly   316 VIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAV 380
            .....::|.||||.|:..||.....|:|:|..|..:.::::... .||.:...|::..||.:|||
 Frog   268 YANMTEMLLAGVDTTSFTLSWATYLLAKNPGIQEAVYQQIVQNF-GKDQVPTAEDVPKMPLVRAV 331

  Fly   381 IKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPE 445
            :|||||.:|...|..|..|:|:::.||.:||||.:.|.......:|..:|..:||.||||:|
 Frog   332 VKETLRLFPVLPGNGRVTQDDLVVGGYFIPKGTQLALCHYSTSYDAECFPAAEEFRPERWIR--- 393

  Fly   446 TGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPF-KTMFLMEPA 509
            :|...:...|..:|||:|.|.|||:||.:|||...:.:|::||.::.:...:... ||..|:.|.
 Frog   394 SGNLERKENFGSIPFGYGIRSCIGRRVAELEMHLLLIQLLQNFEIKPSPQTTTVLPKTHGLLCPG 458

  Fly   510 ITFPFKFTD 518
            .....:|.|
 Frog   459 GKINVRFVD 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	120/451 (27%)
cyp27c1	NP_001011341.1	cytochrome_P450	30..462	CDD:477761	120/449 (27%)