Protein Alignment Cyp12d1-d and Cyp12a5

DIOPT Version :9

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 222/492 - (45%)
• Similarity: 326/492 - (66%)
• Gaps: 14/492 - (2%)

  Fly    40 KTYDEIPRPNKFK-FMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDI 103
            |.::|||:.|... |.::.:|||:::|..:.|...|:|:.||:|..:|||.||...|.|.|.||.
  Fly    45 KPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDF 109

  Fly   104 EMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMY 168
            |:||||||:||.|.|.|.:.|.|...|.|.:..|||::.||.::||..||.:||:.|||:.:|:|
  Fly   110 EVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLY 174

  Fly   169 YEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALT 233
            ::.:|.:|.||:|.||||||..|.|||.:|.:.|:|...||:.:||.|:|:||:|::..||:|..
  Fly   175 FKKMSQVNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATK 239

  Fly   234 LFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAG--E 296
            ||:...:.|..:..|:::||:|:...||..:||.||::....|:.|.:.|..:.|||..:.|  .
  Fly   240 LFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVR 304

  Fly   297 KINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPT 361
            ..:..|:||:|:::|.|||.:|::|:|.||||.|::..:|:||||:|:|:|||:||||::.::|.
  Fly   305 PEHEQSVLEKLLKVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPN 369

  Fly   362 KDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTV-LLGSNVLMKE 425
            |||...|.:||::|||||.|||:.|.||...|..|....|.::||||||.||.| ::..|.|..|
  Fly   370 KDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSE 434

  Fly   426 ATYYPRPDEFLPERWLRD--------PETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVA 482
             .|:|:|.|||||||||:        |....|.: :||.|||||||||||:|||:|::|:|...|
  Fly   435 -EYFPKPTEFLPERWLRNASDSAGKCPANDLKTK-NPFVFLPFGFGPRMCVGKRIVEMELELGTA 497

  Fly   483 KLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDI 519
            :|||||:||||......|::..:..|.|...|||||:
  Fly   498 RLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTDV 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	205/448 (46%)
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	206/451 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445008
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2311
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	10	9.900