Protein Alignment Cyp12d1-d and cyp46a1.2

DIOPT Version :9

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_009292815.1
• Gene: cyp46a1.2 / 393433
• ZFINID: ZDB-GENE-040426-1184
• Length: 501
• Species: Danio rerio
• Alignment Length: 528
• Identity: 124/528 - (23%)
• Similarity: 217/528 - (41%)
• Gaps: 124/528 - (23%)

  Fly    39 HKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAM--------------RKRYGDIYVMPGMF 89
            |:.||.||.|.:..|:....|          ..|.||              .::||.:|
Zfish    32 HQKYDHIPGPPRDNFLLGHSP----------SLTKAMYSDDSLIHDLFLQWAEKYGPVY------ 80

  Fly    90 GRKDWVTTFN-----------TKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGE---VQGL 140
                .:.|.:           ||.|.|        ..:...|...|.|..   :::|:   ..||
Zfish    81 ----RINTLHYIAILVHCPEATKTILM--------SPKYAKDPFSYSRLF---NLFGKRFLGNGL 130

  Fly   141 V-ASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISR 204
            | |..::.|.:.|..::|.|.... ||........::...:::::|:.:.||   |....|.::.
Zfish   131 VTAVDHDIWYRQRRIMDPAFSSSY-LRSLISTFDEMSERLMDKLEEMANNKT---PAVMHDLVNC 191

  Fly   205 LVFESLGLVAFDRQMG-LIRKNRDNSDALTLFQT-----SRD-IFRLTFKLDIQPSMWKII---- 258
            :..:.:..|||...:. |.:|:....:|:.|...     :|| :||      |.|..||:|
Zfish   192 VTLDVICKVAFGVDLNFLTQKDSPFQNAIELCLNGMALDARDPLFR------IFPKNWKLIQQIR 250

  Fly   259 -STPTYRK--------MKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKV 314
             :....||        .|..:.:..:|.:.:|.:.....|:     |.:||:..||::|:
Zfish   251 DAAVLLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKIAEE-----ENVNSSEDLEQMMD----- 305

  Fly   315 AVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRA 379
               ..:....||.:.||..||..::.|.::|:...:.:.|:..::.||..:.||: :..:.||..
Zfish   306 ---NFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKREISNED-LGKLTYLSQ 366

  Fly   380 VIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDP 444
            |:|||||.||...||.|....|:|::|.::|.|.:|:..|.|..:...::..|.:|.|||:  |.
Zfish   367 VLKETLRLYPTAPGTNRWLHEDMIINGIKIPGGCSVMFSSFVSQRLEKFFKDPLKFDPERF--DE 429

  Fly   445 ETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPA 509
            ...|..    :.:.||..|||.|:|:....:|.:..:|||::.|.              |.:.|.
Zfish   430 NAPKPY----YCYYPFALGPRTCLGQVFSQMEAKVVLAKLLQRFE--------------FSLVPG 476

  Fly   510 ITFPFKFT 517
            .:|..|.|
Zfish   477 QSFDIKDT 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	112/486 (23%)
cyp46a1.2	XP_009292815.1	p450	39..495	CDD:278495	120/521 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920