Protein Alignment Cyp12d1-d and Cyp6a23

DIOPT Version :10

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 116/481 - (24%)
• Similarity: 190/481 - (39%)
• Gaps: 111/481 - (23%)

  Fly    71 YTSAMRKRYGDIYVMPG---MFGRKDWVTTFNTKDIEMV----------FRNEGIWPRRDGLDSI 122
            ||...|    .:|...|   .|.|...:|     |:|:|          |.|.||:
  Fly    60 YTKYKR----SVYPFAGFYFFFTRSAVIT-----DLELVKRVLIKDFNHFENRGIF--------- 106

  Fly   123 VYFREHVRPDVYGEVQG-----LVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIER 182
                       |.|:..     |.:.:.:.|..||..:.|.|...:...|:  |:.....|.:|:
  Fly   107 -----------YNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMF--PIIVKVGEEMEK 158

  Fly   183 IKEIR----DPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIF- 242
            |...:    :.:.||:    .|.::|...:.:|..||    ||...:..|.:|..:....|.|.
  Fly   159 IFSAKTTTGEGQVLEI----VDLVARYTADVIGNCAF----GLNCNSLQNPNAEFVTIGKRAIIE 215

  Fly   243 -------------------RLTFKLDIQ--PSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQD 286
                               ||..||::|  ...:..|       ::.|::..|..::|.......
  Fly   216 RRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSI-------VRNTIDYRLRTNEKRHDFMDS 273

  Fly   287 ALE--KRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILF-AGVDATATLLSAVLLCLSKHPDKQ 348
            .:|  ::.|||...:..|..|          ::....|.| ||.:.::|.:...|..|:...|.|
  Fly   274 LIEMYEKEQAGNTEDGLSFNE----------ILAQAFIFFVAGFETSSTTMGFALYELALDQDIQ 328

  Fly   349 AKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSG--YRVPK 411
            .:||.|:.:::...::....|.:|:|.||..|:.||||.||......|..|.|.....  |.:.|
  Fly   329 DQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAK 393

  Fly   412 GTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSP-FTFLPFGFGPRMCIGKRVVDL 475
            ||||::.:..:..:...||.|::|.|||:     |.:.:...| .|:||||.|||.|||.|...:
  Fly   394 GTTVVIPALGIHYDPEIYPEPEKFKPERF-----TDEAIAARPSCTWLPFGEGPRNCIGLRFGLM 453

  Fly   476 EMETTVAKLIRNFHVEFNRDASRPFK 501
            :....:|.|||.:....:.:...|.|
  Fly   454 QACVGLAYLIRGYKFSVSTETQIPMK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	114/476 (24%)
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	113/469 (24%)