Protein Alignment Cyp12d1-d and Cyp11b2

DIOPT Version :9

• Sequence 1: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 128/506 - (25%)
• Similarity: 216/506 - (42%)
• Gaps: 78/506 - (15%)

  Fly    40 KTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIE 104
            |.::.||:.::.|:::......|....::........:..|.|:....  |....|:....:|.|
  Rat    38 KPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRHSA--GGAQIVSVMLPEDAE 100

  Fly   105 MVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYY 169
            .:.:.|.|.|||..|:..|..||     :.|..:|:.......|...|..:||..:.|:.::.:.
  Rat   101 KLHQVESILPRRMHLEPWVAHRE-----LRGLRRGVFLLNGADWRFNRLKLNPNVLSPKAVQNFV 160

  Fly   170 EPLSNINNEFIERIKE-----IRDPKTLEVPE---DFTDEISR--LVFESLGLVAFDRQMGLIRK 224
            ..:..:..:|:|.:|:     .|...|::|.:   ::|.|.|.  |..|.|||:..|.
  Rat   161 PMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDL------- 218

  Fly   225 NRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDA-- 287
               |..:|........:|:.|.:|...|           |.:.|.      .|.::.||:.||
  Rat   219 ---NPGSLKFIHALHSMFKSTTQLLFLP-----------RSLTRW------TSTRVWKEHFDAWD 263

  Fly   288 --LEKRRQAGEKINSNSMLERLMEIDPKVAVIM-------------SLDILFAGVDATATLLSAV 337
              .|...:...|::....|.........||.::             |:::....||.||..|...
  Rat   264 VISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMELTAGSVDTTAIPLVMT 328

  Fly   338 LLCLSKHPDKQAKLREELLSIMPTKDSLL--NEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQN 400
            |..|:::||.|..||:|.|:   .:.|:.  .::.|.|:|.|||.:|||||.||.|....|...:
  Rat   329 LFELARNPDVQQALRQETLA---AEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILNS 390

  Fly   401 DVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPR 465
            |::|..|.||.||.|||....:.:....:|||:.::|:|||....:        |..|.||||.|
  Rat   391 DLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRS--------FQHLAFGFGVR 447

  Fly   466 MCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLM----EPAITF 512
            .|:|:|:.::||...:..:::.|.||..|.........|::    .|.:||
  Rat   448 QCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDVQMAYRFVLMPSSSPVLTF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	120/470 (26%)
Cyp11b2	NP_036670.2	p450	44..498	CDD:278495	124/498 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820