Protein Alignment luna and WT1

DIOPT Version :9

• Sequence 1: NP_001260879.1
• Gene: luna / 2768719
• FlyBaseID: FBgn0040765
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_077744.4
• Gene: WT1 / 7490
• HGNCID: 12796
• Length: 522
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 126/511 - (24%)
• Similarity: 190/511 - (37%)
• Gaps: 110/511 - (21%)

  Fly   133 VLLAAPPSAISPNPS-----------------------------IGSAGNMTPTSISNSSSISSS 168
            :||..|.|...|.|:                             :|:| ..:...:....|..:|
Human     4 LLLQDPASTCVPEPASQHTLRSGPGCLQQPEQQGVRDPGGIWAKLGAA-EASAERLQGRRSRGAS 67

  Fly   169 NSHSNSNGNTTGSSNIIASPLSSLGSGS--TITVSSRNSSAPGIKVRVVQAKNHPGSNARMHLGH 231
            .|.....|:.....|.:...:.|||.|.  .:.||.....||.:...      .||::|...||.
Human    68 GSEPQQMGSDVRDLNALLPAVPSLGGGGGCALPVSGAAQWAPVLDFA------PPGASAYGSLGG 126

  Fly   232 VQDFVLPTLTPPSSPESNLR---SHNYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQPGN 293
            ......|...||..|.|.::   |...|:..|...|:|.......|........:.....|.|.:
Human   127 PAPPPAPPPPPPPPPHSFIKQEPSWGGAEPHEEQCLSAFTVHFSGQFTGTAGACRYGPFGPPPPS 191

  Fly   294 STPATAILRFTSQSNPTMTQLQQQQQQLAVQHLSISPQALGHSNI---GSNSPKSSSSSSSNSSN 355
            ...:.....|.:.  |.:....:.|..:..|         |:|.:   |:.|...:.|..:....
Human   192 QASSGQARMFPNA--PYLPSCLESQPAIRNQ---------GYSTVTFDGTPSYGHTPSHHAAQFP 245

  Fly   356 SSSSSHSSSSSISGSSDQPTHSNIPRSTIVRLTTANGKPGAAGISLA------RVIQMQNN---- 410
            :.|..|.......||..:..:| :|.......|..:...|:..:.|.      .:.||.:.
Human   246 NHSFKHEDPMGQQGSLGEQQYS-VPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECM 309

  Fly   411 --GNANVAAVLSAAANSGSSNS---NSNSSSSNTSSNSINTATP-----QQQV------------ 453
              ...|:.|.|...| :|||:|   ....|:.:|...|.|..||     |.::
Human   310 TWNQMNLGATLKGVA-AGSSSSVKWTEGQSNHSTGYESDNHTTPILCGAQYRIHTHGVFRGIQDV 373

  Fly   454 -----LSQRSEKSANGSSKPHHPRQHHSDHSPDAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTG 513
                 ::....:||:.:|                ::|...|.:.||.|.|.|.|||:.|.|.|||
Human   374 RRVPGVAPTLVRSASETS----------------EKRPFMCAYPGCNKRYFKLSHLQMHSRKHTG 422

  Fly   514 EKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            ||||:|.::.||.||:|||:|.||.|:|||.|||:|:.|.|.|||||||..|.:.|
Human   423 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	45/103 (44%)
		C2H2 Zn finger	489..511	CDD:275368	11/21 (52%)
		zf-H2C2_2	503..>519	CDD:290200	11/15 (73%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..558	CDD:290200	14/24 (58%)
		C2H2 Zn finger	549..569	CDD:275368	11/19 (58%)
WT1	NP_077744.4	WT1	74..394	CDD:308009	66/354 (19%)
		COG5048	386..>514	CDD:227381	52/109 (48%)
		C2H2 Zn finger	401..420	CDD:275368	10/18 (56%)
		C2H2 Zn finger	428..450	CDD:275368	12/21 (57%)
		C2H2 Zn finger	458..478	CDD:275368	11/19 (58%)
		C2H2 Zn finger	489..511	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010