DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment luna and Klf14

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001128565.1	Gene:	Klf14 / 619665	MGIID:	3577024	Length:	325	Species:	Mus musculus

Alignment Length:	284	Identity:	87/284 - (30%)
Similarity:	123/284 - (43%)	Gaps:	63/284 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 LSISPQALGHSNIGSNSPKSSSSSSSNSSNSSSSSHSSSSSISGSSDQ---PTHSNIPRSTIVRL 387
            :|:|.:|:.|..  :..|:.:|:::  .|...:.|..|:...:||...   |....:|
Mouse    17 VSMSTRAVLHRR--ATDPEGASAAA--VSEVGAVSRESAGKGTGSRGVLWIPPVLQVP------- 70

  Fly   388 TTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSNSSSSNTS-------SNSIN 445
            |.:.|:...|...||          |:..|.||..|.......:..:..::||       |:...
Mouse    71 TPSPGEGDGAPHLLA----------ASALADLSCGAREDFREDSEEAPCASTSCFEPTWCSSPTG 125

  Fly   446 TATPQQQVLS-------------------QRSEKSANGSSKPH-----------HPRQHHSDHSP 480
            .:.|.|....                   :.||:..:....|.           .|.......:|
Mouse   126 GSEPTQAFFEDELSDAESSCSDSAILDAPEASEEPDDSGEVPEGPPGARPAPSTGPTYRRRQITP 190

  Fly   481 DAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAK 545
            .:||  |:|.|.||.|.|.||||||:||||||||:|:.|.|..|:.:|.|||||.||||.|||.|
Mouse   191 ASKR--HQCSFHGCNKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEK 253

  Fly   546 PFKCRNCDRCFSRSDHLALHMKRH 569
            .|.|..|.:.|||||||..|.:||
Mouse   254 RFSCPLCPKQFSRSDHLTKHARRH 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	51/133 (38%)
		C2H2 Zn finger	489..511	CDD:275368	15/21 (71%)
		zf-H2C2_2	503..>519	CDD:290200	12/15 (80%)
		C2H2 Zn finger	519..541	CDD:275368	13/21 (62%)
		zf-H2C2_2	533..558	CDD:290200	14/24 (58%)
		C2H2 Zn finger	549..569	CDD:275368	10/19 (53%)
Klf14	NP_001128565.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..196		7/44 (16%)
		COG5048	198..>283	CDD:227381	50/80 (63%)
		C2H2 Zn finger	200..219	CDD:275368	13/18 (72%)
		zf-H2C2_2	211..238	CDD:290200	16/26 (62%)
		C2H2 Zn finger	227..249	CDD:275368	13/21 (62%)
		zf-H2C2_2	241..266	CDD:290200	14/24 (58%)
		C2H2 Zn finger	257..277	CDD:275368	10/19 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..325		4/8 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930