DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment luna and klf5l

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001035016.2	Gene:	klf5l / 562670	ZFINID:	ZDB-GENE-060312-34	Length:	401	Species:	Danio rerio

Alignment Length:	313	Identity:	120/313 - (38%)
Similarity:	148/313 - (47%)	Gaps:	74/313 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 LNPQPGNSTPATAILRFTSQSNPTMTQLQQQQQQLAVQHLSISPQ--ALGHSNIGSNSPKSSSSS 349
            :..:||...|...      |:.|..|.:....|  .|..|.|.|:  .....:||...| |:...
Zfish   131 IKTEPGLDEPCGI------QTLPEFTSVFSVPQ--TVNSLFIKPEIPVTDELHIGPQQP-SAYQM 186

  Fly   350 SSNSSNSSSSSHSSSSSISGSSDQPTHSNIPRSTIVRLTTANGKPGAAGISLARVIQMQNNGNAN 414
            ..:||:.::.:.|.|.|::|.                     |.||...:            |.|
Zfish   187 PVSSSDLTTMTFSHSQSMNGI---------------------GAPGRTML------------NLN 218

  Fly   415 VAAVLSAAA----------NSGSSNS------NSNSSSSNTSSNSINTATPQQQVLSQRSEKSAN 463
            ..|:.:.:|          ||...:|      ||...|....:..|.:..|.....::...|.
Zfish   219 TVALTAQSAEFVMPESFTYNSPQPHSLPPSPPNSQPGSPENQAELITSVAPPPPYQARLGMKV-- 281

  Fly   464 GSSKPHH------------PRQHHSDHSPDAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKP 516
            |...||.            ||.:..::....|||||.|.|.||.|||||||||||||||||||||
Zfish   282 GQMTPHSMIMAHGQGILTGPRYNRRNNPELEKRRIHHCDFQGCNKVYTKSSHLKAHQRTHTGEKP 346

  Fly   517 YKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            |:||||||:||||||||||||||||||||||||..|.||||||||||||||||
Zfish   347 YRCSWEGCDWRFARSDELTRHYRKHTGAKPFKCIACSRCFSRSDHLALHMKRH 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	72/115 (63%)
		C2H2 Zn finger	489..511	CDD:275368	18/21 (86%)
		zf-H2C2_2	503..>519	CDD:290200	15/15 (100%)
		C2H2 Zn finger	519..541	CDD:275368	20/21 (95%)
		zf-H2C2_2	533..558	CDD:290200	21/24 (88%)
		C2H2 Zn finger	549..569	CDD:275368	16/19 (84%)
klf5l	NP_001035016.2	COG5048	<226..>401	CDD:227381	93/176 (53%)
		zf-C2H2	317..341	CDD:278523	19/23 (83%)
		C2H2 Zn finger	324..341	CDD:275368	15/16 (94%)
		zf-H2C2_2	333..>349	CDD:290200	15/15 (100%)
		zf-C2H2	347..371	CDD:278523	21/23 (91%)
		C2H2 Zn finger	349..371	CDD:275368	20/21 (95%)
		zf-H2C2_2	363..388	CDD:290200	21/24 (88%)
		C2H2 Zn finger	379..399	CDD:275368	16/19 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.970