DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment luna and Spps

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster

Alignment Length:	680	Identity:	166/680 - (24%)
Similarity:	248/680 - (36%)	Gaps:	222/680 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 EELKIKEQHLDTIST----TSSVSSNCSGTSWDSNGSQALSCSVLVKQERIDEEDDDVGCDDKLS 132
            ::.:.::.|..|:..    |::..:|.||.: :|..:..|..|:.:.                 .
  Fly   183 QQQQAQQVHQGTVQQQAQGTNASGANGSGVT-NSGTAGQLPGSITIP-----------------G 229

  Fly   133 VLLAAPPSAISPNPSIGSAGNMTPTSISNSSSISSSNSHSNSNGNTTGSSNIIASPLSSL----- 192
            ..|..|.|..:.|..:|:..|:       |:.:....|....||.......::..|..::
  Fly   230 TNLQIPTSVAAANGLLGNISNI-------SNLLGGGQSIKLENGQLQMRPQLVQFPAPAMPQQQQ 287

  Fly   193 ----------GSGSTI------TVSSRNSSAPGIKVRVVQAKN-HPGSNARMHL----------- 229
                      .:|.||      .|.:..:|:.|:: .::||:: ...|.::|.:
  Fly   288 TVAVQIPVQTANGQTIYQTVHVPVQAAATSSGGLQ-NLMQAQSLQMPSASQMQIIPQFSQIAQIV 351

  Fly   230 ---GHVQDFVLPTLTPPSSPESNL----RSH-NYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQ 286
               |.:|...|....|...|.:|:    ..| ...||::........|||||.||||.|||||||
  Fly   352 TPNGQIQQVQLAMPYPQLPPNANIIHIQNPHQQQQQQVQQQQQQQQAQQQQQAQQQQAQQQQQQQ 416

  Fly   287 LNPQ--------------------------------------------PGNSTPATA-------- 299
            :..|                                            |...|||.|
  Fly   417 VQAQHQQLLQAISDASAGGQLPPNQPITITNAQGQQLTVIPAQLRPNAPTAPTPAPAGVPTPMQM 481

  Fly   300 --ILRFTSQSNPTMTQL----------------QQQQQQLAVQHLSIS----------------- 329
              :.....|:.|.:.|:                ||...||.:.|..:.
  Fly   482 PNLQALPIQNIPGLGQVQIIHANQLPPNLPANFQQVLTQLPMSHPQVQTQGQVQVMPKQEPQSPT 546

  Fly   330 ----------PQALGHSNIGSNSPKSSSSSSSNS------------SNS-SSSSHSSSSSISGSS 371
                      |...|..:...|.|..:|:.::.|            ||| ||.|..:|..|:...
  Fly   547 QMITSIKQEPPDTFGPISATGNPPAPASTPNTASPQQQQIKFLHTESNSLSSLSIPASIQITALP 611

  Fly   372 DQPTHS-NIPRST--IVRLTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSN 433
            .|.|:: |.|.:|  |.....|..|..|...|..::......|  .|.:|.:.|..:.:|
  Fly   612 QQATNTPNTPATTQPIPVSLPARSKVNAVTTSSTQITIAPTGG--QVVSVTTQARGATAS----- 669

  Fly   434 SSSSNTSSNSINTATPQQQVLSQR-------------SEKSANGSSKPHHPR-----------QH 474
            ..|:|||:.:|  .||.|..|:..             ...:|.|..||...|           :.
  Fly   670 IRSTNTSTTTI--TTPSQSHLNMNISVASVGGAATGGGGGTATGEPKPRLKRVACTCPNCTDGEK 732

  Fly   475 HSDHSPDAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYR 539
            |||     |:|.|.|...||.|||.|:|||:||.|.||||:|:.|||..|..||.|||||.||.|
  Fly   733 HSD-----KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRR 792

  Fly   540 KHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            .|||.|.|:|:.|::.|.|||||:.|:|.|
  Fly   793 THTGEKRFQCQECNKKFMRSDHLSKHIKTH 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	51/127 (40%)
		C2H2 Zn finger	489..511	CDD:275368	13/21 (62%)
		zf-H2C2_2	503..>519	CDD:290200	10/15 (67%)
		C2H2 Zn finger	519..541	CDD:275368	14/21 (67%)
		zf-H2C2_2	533..558	CDD:290200	13/24 (54%)
		C2H2 Zn finger	549..569	CDD:275368	10/19 (53%)
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	54/103 (52%)
		C2H2 Zn finger	742..764	CDD:275368	13/21 (62%)
		zf-H2C2_2	756..783	CDD:290200	16/26 (62%)
		C2H2 Zn finger	772..794	CDD:275368	14/21 (67%)
		zf-H2C2_2	786..809	CDD:290200	12/22 (55%)
		zf-C2H2	800..822	CDD:278523	11/21 (52%)
		C2H2 Zn finger	802..822	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010