DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment luna and Sp6

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001102303.1	Gene:	Sp6 / 363672	RGDID:	1306768	Length:	376	Species:	Rattus norvegicus

Alignment Length:	433	Identity:	106/433 - (24%)
Similarity:	161/433 - (37%)	Gaps:	144/433 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 IIASPLSSLGSGSTITVSSRNSSAPGIKVRVVQAKNHPGSNARMHLGHVQDFVLPTLTPPSSPES 248
            ::.:...||||..|   .:.:||.|.:.::.:|.          :.||            :|||:
  Rat     1 MLTAVCGSLGSQHT---DAPHSSPPRLDLQPLQT----------YQGH------------TSPEA 40

  Fly   249 NLRSHNYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQ---------PGNSTPATAILRFT 304
            .    :|...|:..:|.:|                  .|.|:         ||.|:..|.
  Rat    41 G----DYPSPLQPGELQSL------------------PLGPEVDFSQGYELPGASSRVTC----- 78

  Fly   305 SQSNPTMTQLQQQQQQLAVQHLSISPQALGHSNIGSNSPKSSSSSSSNSSNSSSSSHSSSSSISG 369
                                           .::.|:||.:....|.......|..:.|..
  Rat    79 -------------------------------EDLESDSPLAPGPFSKLLQPDMSHHYESWF---- 108

  Fly   370 SSDQPTHSNI---------PRSTIVRL------TTANGKPGAAGISLARVIQMQNNGNANVAA-- 417
               :|||...         |.::.:.|      .|:.|.|||...:|...:     |:..:.|
  Rat   109 ---RPTHPGTEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQPALGGYV-----GDHQLCAPP 165

  Fly   418 -------VLSAAAN-------SGSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEKSANGSSKP 468
                   :|.||..       .|:....:.:..|....:|::.|...:.  |:||...::|.:..
  Rat   166 PHPHPHHLLPAAGGQHLLGPPDGAKVLEAAAPESQGLDSSLDAAARPKG--SRRSVPRSSGQTVC 228

  Fly   469 HHPRQHHSDH-----SPDA--KRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEW 526
            ..|....::.     .||.  |:.:|.|...||.|.|.|:||||||.|.|:|::|:.|:|..|..
  Rat   229 RCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGK 293

  Fly   527 RFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            ||.|||||.||.:.|||.|.|.|..|.|.|.||||||.|||.|
  Rat   294 RFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTH 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	46/110 (42%)
		C2H2 Zn finger	489..511	CDD:275368	13/21 (62%)
		zf-H2C2_2	503..>519	CDD:290200	9/15 (60%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..558	CDD:290200	13/24 (54%)
		C2H2 Zn finger	549..569	CDD:275368	13/19 (68%)
Sp6	NP_001102303.1	C2H2 Zn finger	259..278	CDD:275368	12/18 (67%)
		COG5048	<261..>336	CDD:227381	44/74 (59%)
		zf-H2C2_2	270..297	CDD:290200	14/26 (54%)
		C2H2 Zn finger	286..308	CDD:275368	12/21 (57%)
		zf-H2C2_2	300..323	CDD:290200	12/22 (55%)
		zf-C2H2	314..336	CDD:278523	14/21 (67%)
		C2H2 Zn finger	316..336	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344913
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930