DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment luna and Sp1

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	135/463 - (29%)
Similarity:	187/463 - (40%)	Gaps:	112/463 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 SPN-PSIG--------------SAGNMTPTSISNSSSISSSNSHSNSNGNTTGSS-----NIIAS 187
            ||| |:.|              |||..:|.:||.:||.|||.|....:..:..||     ||.||
  Fly    81 SPNSPAAGSSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITAS 145

  Fly   188 -PLSS----LGSGSTITVSSRNSSAPGIKVRVVQAKNHPGSNARMHLGHVQDFVLPTLTPPSSPE 247
             ||:|    :|.|||.:.||.:.|         |:.:...:.|..:.|        .|..|::..
  Fly   146 RPLASSCAAVGGGSTGSSSSASGS---------QSSSTASAVAAAYGG--------DLYFPNTST 193

  Fly   248 SNLRSHNYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQPGNSTPATAILRFTSQSNPTMT 312
            ||:.:|:..|.|                               .|......|........:|...
  Fly   194 SNMDNHHMHQGL-------------------------------LGKVEAGAAAFGGVYSRHPYDW 227

  Fly   313 QLQQQQQQLAVQHLSISPQALG----HSNIGSNSPKSSSSSSSNSSNSSSSSHSS--SSSISGSS 371
            ...      ||.|...:....|    ||..||......:...|..:|.:|.::||  |.|:.||.
  Fly   228 PFN------AVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLLGSG 286

  Fly   372 DQPTHSNIPRSTIVRLTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSNSSS 436
                 .::.:.|...:....|.....|:.:.......::.:|..||..:|||.:|.|....:.|
  Fly   287 -----QHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPS- 345

  Fly   437 SNTSSNSINTATPQQQVLSQRSEKSANGSSKPHHPRQHHSDHSPDA-----KRRIHKCQFLGCKK 496
                       ||     |.||::...|.:....|....::....|     |:.||.|...||.|
  Fly   346 -----------TP-----SPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGK 394

  Fly   497 VYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDH 561
            ||.|:||||||.|.||||:|:.|:|..|..||.|||||.||.|.|||.|.|.|..|::.|.||||
  Fly   395 VYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDH 459

  Fly   562 LALHMKRH 569
            ||.|:|.|
  Fly   460 LAKHVKTH 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	49/108 (45%)
		C2H2 Zn finger	489..511	CDD:275368	14/21 (67%)
		zf-H2C2_2	503..>519	CDD:290200	11/15 (73%)
		C2H2 Zn finger	519..541	CDD:275368	13/21 (62%)
		zf-H2C2_2	533..558	CDD:290200	13/24 (54%)
		C2H2 Zn finger	549..569	CDD:275368	11/19 (58%)
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	13/18 (72%)
		zf-H2C2_2	401..428	CDD:290200	16/26 (62%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	12/22 (55%)
		zf-C2H2	445..467	CDD:278523	12/21 (57%)
		C2H2 Zn finger	447..467	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455429
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I1951
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990