DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment luna and Klf17

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_038967113.1	Gene:	Klf17 / 298449	RGDID:	1307711	Length:	383	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	107/374 - (28%)
Similarity:	144/374 - (38%)	Gaps:	107/374 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 IQQQQQQQQQQQQQQQQQQLNP---QPGNS-------TPATAIL--------------------- 301
            ::|..:||...|.....:.|.|   .||:|       .||...|
  Rat     1 MEQDNEQQAMHQSPMDNEMLMPVSHMPGSSGNSGFHQPPAPQYLPELMRPYMASAEEFRCSEGGW 65

  Fly   302 -------------RFTSQSNPTMTQLQQQQQQLAVQHLSISPQALGHSNIGSNS-------PKSS 346
                         |..||..||.:|...|:                  :||..|       |.:.
  Rat    66 EPQFIRSLPESGARCPSQLIPTPSQNYCQR------------------SIGRGSHVMPVGNPGTL 112

  Fly   347 SSSSSNSSNSSSSSHSSSSSISGSSDQPTHSNIPR-----STIVRLTTANGKPG---AAGISLAR 403
            ..:.|.|.|..|....||.:..|.|.. ||||.|.     |..|..||.:.|||   ..|:..|.
  Rat   113 GVAISFSENLMSQGGLSSPASCGVSVM-THSNAPTMPYSVSPTVPATTGSLKPGIFLVPGMPSAE 176

  Fly   404 -------VIQMQNNGNAN-VAAVLSAAANSGSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEK 460
                   :.||.::.|.. |:|.........|.:|.:..|:...........||..|  .:.:..
  Rat   177 THAVTPYMNQMLHSVNPEMVSARFQQLLPIDSQDSLATQSNVQEGPFMCEQPTPAPQ--ERETAS 239

  Fly   461 SANGSSKPHHPRQHHSDHSPDAKR----RIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSW 521
            ::.|:::               :|    |.:.|.:..|.|.|||.|||.:|.|.|||||||.|.|
  Rat   240 TSRGATR---------------RRSLVLRPYVCSYDDCGKAYTKRSHLVSHLRKHTGEKPYICDW 289

  Fly   522 EGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRHM 570
            :||:|||.|||||.||.|.||..:|.||..|:|.|.|||||..|.:.|:
  Rat   290 KGCKWRFFRSDELGRHKRIHTRYRPHKCDECNREFMRSDHLRQHKRTHL 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	44/107 (41%)
		C2H2 Zn finger	489..511	CDD:275368	11/21 (52%)
		zf-H2C2_2	503..>519	CDD:290200	11/15 (73%)
		C2H2 Zn finger	519..541	CDD:275368	15/21 (71%)
		zf-H2C2_2	533..558	CDD:290200	13/24 (54%)
		C2H2 Zn finger	549..569	CDD:275368	10/19 (53%)
Klf17	XP_038967113.1	KLF17_N	1..259	CDD:410567	60/293 (20%)
		zf-C2H2	255..279	CDD:395048	11/23 (48%)
		C2H2 Zn finger	260..279	CDD:275368	10/18 (56%)
		C2H2 Zn finger	287..309	CDD:275368	15/21 (71%)
		zf-H2C2_2	304..324	CDD:404364	10/19 (53%)
		zf-C2H2	315..337	CDD:395048	11/21 (52%)
		C2H2 Zn finger	317..337	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030