DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment luna and klf-3

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001022205.1	Gene:	klf-3 / 191713	WormBaseID:	WBGene00003480	Length:	315	Species:	Caenorhabditis elegans

Alignment Length:	146	Identity:	72/146 - (49%)
Similarity:	93/146 - (63%)	Gaps:	20/146 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 NSGSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEKSANGSSKPHHPRQHHSDHSPDAKRRIHK 488
            ::|..:|..:|.||.|||        ::..|.::|...:|            ..:..|.|..:|.
Worm   187 HNGELDSTRSSPSSTTSS--------ERSPLQRKSRIESN------------KRNPTDKKFVVHA 231

  Fly   489 CQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCD 553
            |.:.||.|.|:||||||||:|||:||||:.|.|:.|.|:||||||||||.|||||.|||:|..||
Worm   232 CTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHTGDKPFRCSLCD 296

  Fly   554 RCFSRSDHLALHMKRH 569
            |.|:|||||:||||||
Worm   297 RNFARSDHLSLHMKRH 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	52/103 (50%)
		C2H2 Zn finger	489..511	CDD:275368	14/21 (67%)
		zf-H2C2_2	503..>519	CDD:290200	12/15 (80%)
		C2H2 Zn finger	519..541	CDD:275368	15/21 (71%)
		zf-H2C2_2	533..558	CDD:290200	18/24 (75%)
		C2H2 Zn finger	549..569	CDD:275368	14/19 (74%)
klf-3	NP_001022205.1	C2H2 Zn finger	235..254	CDD:275368	13/18 (72%)
		C2H2 Zn finger	262..284	CDD:275368	15/21 (71%)
		zf-H2C2_2	276..301	CDD:290200	18/24 (75%)
		C2H2 Zn finger	292..312	CDD:275368	14/19 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010