DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment luna and sptf-1

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001021465.1	Gene:	sptf-1 / 172909	WormBaseID:	WBGene00009743	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	397	Identity:	96/397 - (24%)
Similarity:	141/397 - (35%)	Gaps:	128/397 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 AISPN-PSIGSAGNMTPTSISNSSSISSSNSHSNSNGNTTGSSNIIAS-----------PLSSLG 193
            |.||. ||..||...|..:...||.|...|:. |...|.|.::::..|           |||.|
Worm     4 ASSPRIPSRRSAPYFTSLAFFGSSYIKVKNNR-NKMLNPTDAASVALSFSVPFQMSGENPLSKL- 66

  Fly   194 SGSTITVSSRNSSAPG--IKVRVVQAKNHPGSNARMHLGHVQDFVLPTLTPPSSPESNLRSHNYA 256
                  |...|...||  ||::...||             .:..:|||.....||  .|.:.|:.
Worm    67 ------VEHCNKFVPGADIKMKAEPAK-------------PESLLLPTDMNAYSP--YLATPNWW 110

  Fly   257 QQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQPGNSTPATAILRFTSQSNPTMTQLQQQQQQL 321
            ..                               |.|           ..|..||:|
Worm   111 VD-------------------------------QTG-----------WPQLYPTVT--------- 124

  Fly   322 AVQHLSISPQALGHSNIGSNSPKSSSSSSSNSSNSSSSSHSSSSSISGSSDQPTHSNIPRSTIVR 386
            ....:.:....|..|.:|.    ..|||.|..::...:..::.|:::.:|.|.|         :.
Worm   125 TASSVDVYQNYLASSQLGG----LLSSSVSAVASQLPAGINAQSALNITSQQRT---------IA 176

  Fly   387 LTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSNSSSSNTSSNSINTATPQQ 451
            .:..:.||.|:..|:..|:...|           ::|||..|:.:.:.|:..||.:......|
Worm   177 KSFQHTKPMASSSSIPSVLTASN-----------SSANSLVSSGSESVSARGTSGSGGTGKYP-- 228

  Fly   452 QVLSQRSEKSANGSSKPHHPRQHHSD-HSPDA----KRRIHKCQFLGCKKVYTKSSHLKAHQRTH 511
                  |.::||   |...|..|..: ..|:|    ||.:|.|...||.|||.||||||||.|.|
Worm   229 ------SSRTAN---KCECPNCHEIEKFGPNAIAARKRGVHNCHIAGCGKVYNKSSHLKAHLRWH 284

  Fly   512 TGEKPYK 518
            :||:..|
Worm   285 SGERQMK 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	30/69 (43%)
		C2H2 Zn finger	489..511	CDD:275368	15/21 (71%)
		zf-H2C2_2	503..>519	CDD:290200	10/16 (63%)
		C2H2 Zn finger	519..541	CDD:275368	96/397 (24%)
		zf-H2C2_2	533..558	CDD:290200
		C2H2 Zn finger	549..569	CDD:275368
sptf-1	NP_001021465.1	zf-C2H2	260..284	CDD:333835	16/23 (70%)
sptf-1	NP_001021465.1	C2H2 Zn finger	262..284	CDD:275370	15/21 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030