DRSC/TRiP Functional Genomics Resources

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Protein Alignment luna and Klf5

DIOPT Version :9

Sequence 1:NP_001260879.1 Gene:luna / 2768719 FlyBaseID:FBgn0040765 Length:570 Species:Drosophila melanogaster
Sequence 2:NP_033899.2 Gene:Klf5 / 12224 MGIID:1338056 Length:446 Species:Mus musculus


Alignment Length:355 Identity:125/355 - (35%)
Similarity:170/355 - (47%) Gaps:61/355 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   237 LPTLTPPSSPESNLRSHNYAQQLEANDLAALIQQQQQQQQQQQQQQQQQQLNPQPGNSTPATAIL 301
            ||.:|       :||:..|..|      ...:.|.:.:.......|.:....|.|  ..|..|:.
Mouse   129 LPDIT-------HLRTGLYKSQ------RPCVTQIKTEPVTIFSHQSESTAPPPP--PAPTQALP 178

  Fly   302 RFTSQSNPTMTQLQQQQ-------QQLAVQ--HLSISPQALGHSNIGSNSPKSSSSSSSNSSNSS 357
            .|||..:...|....|:       |:|.:.  |||: |...||.....|:|.....||:|.:...
Mouse   179 EFTSIFSSHQTTAPPQEVNNIFIKQELPIPDLHLSV-PSQQGHLYQLLNTPDLDMPSSTNQTAVM 242

  Fly   358 SSSHSSSSSISGSSDQPTHSNIPRSTIVRLTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAA 422
            .:.:.|.:.::     |..|.:|::::.:.   .|.|.......::.:..|             |
Mouse   243 DTLNVSMAGLN-----PHPSAVPQTSMKQF---QGMPPCTYTMPSQFLPQQ-------------A 286

  Fly   423 ANSGSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEKSA------------NGSSKPHHPRQHH 475
            .....|..:|...|.:..:..:...||.....:..:.|.|            |..:.|  |.:::
Mouse   287 TYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPTLP--PVRYN 349

  Fly   476 SDHSPD-AKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYR 539
            ...:|| .|||||.|.:.||.||||||||||||.|||||||||||:||||:||||||||||||||
Mouse   350 RRSNPDLEKRRIHFCDYNGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYR 414

  Fly   540 KHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            ||||||||:|..|.|.||||||||||||||
Mouse   415 KHTGAKPFQCMVCQRSFSRSDHLALHMKRH 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lunaNP_001260879.1 COG5048 <455..>559 CDD:227381 69/116 (59%)
C2H2 Zn finger 489..511 CDD:275368 16/21 (76%)
zf-H2C2_2 503..>519 CDD:290200 14/15 (93%)
C2H2 Zn finger 519..541 CDD:275368 19/21 (90%)
zf-H2C2_2 533..558 CDD:290200 19/24 (79%)
C2H2 Zn finger 549..569 CDD:275368 15/19 (79%)
Klf5NP_033899.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..69
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q13887 107..115
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 284..310 5/38 (13%)
Interaction with WWP1. /evidence=ECO:0000250 313..317 1/3 (33%)
COG5048 338..>422 CDD:227381 60/85 (71%)
C2H2 Zn finger 367..386 CDD:275368 15/18 (83%)
zf-H2C2_2 378..>395 CDD:290200 15/16 (94%)
C2H2 Zn finger 394..416 CDD:275368 19/21 (90%)
zf-H2C2_2 408..433 CDD:290200 19/24 (79%)
C2H2 Zn finger 424..444 CDD:275368 15/19 (79%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167841539
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
54.900

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