DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment luna and Klf9

DIOPT Version :9

Sequence 1:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_476559.2	Gene:	Klf9 / 117560	RGDID:	70934	Length:	244	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	78/225 - (34%)
Similarity:	108/225 - (48%)	Gaps:	37/225 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 SISGSSDQPTHSNIPRSTIVRL-----TTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANS 425
            |||..:..|.|...|.:..:||     |..:|.||...              .:...:::.|.:.
  Rat    17 SISNRAAVPEHGGAPDAERLRLPEREVTKEHGDPGDTW--------------KDYCTLVTIAKSL 67

  Fly   426 GSSNSNSNSSSSNTSSNSINTATPQQQVLSQRSEKSANGSSKPHHPRQHHSD----------HS- 479
            ...|......:.:..|:|:.  :|.:.:.|.....:.:|||..|.|.:....          ||
  Rat    68 LDLNKYRPIQTPSVCSDSLE--SPDEDIGSDSDVTTESGSSPSHSPEERQDSGSAPSPLSLLHSG 130

  Fly   480 -----PDAKRRIHKCQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYR 539
                 ..|..:.|||.:.||.|||.||||||||.|.||||:|:.|:|..|..:|:||||||||||
  Rat   131 VASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYR 195

  Fly   540 KHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
            .|||.|.|:|..|::.|.|||||..|.:||
  Rat   196 THTGEKQFRCPLCEKRFMRSDHLTKHARRH 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	53/119 (45%)
		C2H2 Zn finger	489..511	CDD:275368	15/21 (71%)
		zf-H2C2_2	503..>519	CDD:290200	11/15 (73%)
		C2H2 Zn finger	519..541	CDD:275368	14/21 (67%)
		zf-H2C2_2	533..558	CDD:290200	15/24 (63%)
		C2H2 Zn finger	549..569	CDD:275368	9/19 (47%)
Klf9	NP_476559.2	KLF9_N	3..144	CDD:409239	26/142 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..51		7/26 (27%)
		COG5048	<78..234	CDD:227381	64/150 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..143		12/65 (18%)
		C2H2 Zn finger	145..167	CDD:275368	15/21 (71%)
		C2H2 Zn finger	175..197	CDD:275368	14/21 (67%)
		C2H2 Zn finger	205..225	CDD:275368	9/19 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840