Protein Alignment Ir41a and Ir75b

DIOPT Version :10

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 672
• Identity: 132/672 - (19%)
• Similarity: 237/672 - (35%)
• Gaps: 193/672 - (28%)

  Fly    33 EFQLLHKSDYISFVGINIKSFDDNGGHYIIDTGLKKKELQNKHLFLDELVIKIIISIEVTHCETF 97
            :||.||.         :|:..||...|.|:..|          :|||....|....:::...:.|
  Fly    43 QFQPLHS---------DIQLNDDFLNHNILKLG----------VFLDINCDKSGTVLDMASAKRF 88

  Fly    98 -------VVFDKDIDRFV--NAFNKASVYSIWRSLHNKFVFAHI--ANESPESRNHFFEDQPNIL 151
                   :::|:.::..|  :.|.:|.:          ||.|.:  ....|.|:|....|..|
  Fly    89 FSHRYHWLIYDRSMNFSVLESHFKEAQI----------FVDADVTYVTHDPFSKNFLLYDVYN-- 141

  Fly   152 FVVRDHSSASSFDIKTNKFVGRKAENPSQMILVDRYLA---SEQRFQFGKSLFADKLNNLQGREV 213
               :........:|..::.:.....|    ..|:|||:   :....|..||     ...|..|..
  Fly   142 ---KGRQLGGELNITADREIFCNKTN----CRVERYLSELYTRSALQHRKS-----FTGLTMRAT 194

  Fly   214 IIAGFDYPPYTVIKHNMSTNAQDMGVSGESDFKN----VYID-----GTETRIVLNFCEQFNCTI 269
            .:.       |.:..|:|       :....||.|    :.:|     |.:.|..|.  :..:|..
  Fly   195 AVV-------TALPLNVS-------IKEIFDFMNSKYRIQLDTYARLGYQARQPLR--DMLDCKF 243

  Fly   270 QIDSSAANDWGKVYPNMSGDGALGMLINRKADICIGA-MYSWYEDYTYLDLSMYLVRSGIT---- 329
            :.  ...:.|..  .|.:| |.:|.||..|||:.|.. :||:       |.:::|  ..||
  Fly   244 KY--IFRDRWSD--GNATG-GMIGDLILDKADLAIAPFIYSF-------DRALFL--QPITKFSV 294

  Fly   330 ----CL------VPAPLRLTSWYLPLEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYR 384
                |:      |.|.|..|.:   |:||...:|....|.|......|.:.:..|:        |
  Fly   295 FREICMFRNPRSVSAGLSATEF---LQPFSGGVWLTFALLLLLAGCLLWVTFILER--------R 348

  Fly   385 EGW-----WTC-TSFGVCTTFKLFI---SQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLAS 440
            :.|     .:| .|||.......::   |..|....::|.|...|...:...::::.:.|..:.|
  Fly   349 KQWKPSLLTSCLLSFGAGCIQGAWLTPRSMGGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKS 413

  Fly   441 ILTIPSMDEAADT----------VTRLRFHRLQWAANSEAWVSAIRASDEALVKDILYNFHIY-- 493
              .|.::.:.||:          .||:                .:..|:|..|:| ||...:.
  Fly   414 --NIRTLQQLADSNLDVGIEPTVYTRI----------------YVETSEEPDVRD-LYRKKVLGS 459

  Fly   494 --SDDEL-------LRLAQDQHMRIGFT-VERLPFGH-FAIGNYLGPQAIDQLVIMKDDIYFQYT 547
              |.|::       :...:||.   ||. :..:..|: |...::|..|..:...|...|....:|
  Fly   460 KRSPDKIWIPTEAGVLSVRDQE---GFVYITGVATGYEFVRKHFLAHQICELNEIPLRDASHTHT 521

  Fly   548 VAFVPRLWPLLDKLNTLIYSWHSSGFDKYWEYRVVADNLNLKIQQQVQET-MTGTKDIGPVPLGM 611
            |......:..|.||:               |.|::...::.|.::...|| :...:....|.:|:
  Fly   522 VLAKRSPYAELIKLS---------------ELRMLETGVHFKHERSWMETKLHCYQHNHTVAVGL 571

  Fly   612 SNFAGFIIVWILGSAIATLTFL 633
             .:|..:.:.:||:.|..:..|
  Fly   572 -EYAAPLFIILLGAIILCMGIL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	16/61 (26%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	22/77 (29%)
		Lig_chan	343..584	CDD:459656	51/286 (18%)