DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir41a and grin3ba

DIOPT Version :9

Sequence 1:	NP_995744.4	Gene:	Ir41a / 2768714	FlyBaseID:	FBgn0040849	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	XP_021323058.1	Gene:	grin3ba / 566411	ZFINID:	ZDB-GENE-070912-354	Length:	1118	Species:	Danio rerio

Alignment Length:	392	Identity:	86/392 - (21%)
Similarity:	145/392 - (36%)	Gaps:	100/392 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 GALGMLINRKADIC-----IGAMYSWYEDYT--YLDLSM-YLVRSGITCLVPAPLRLTSWYLPLE 346
            |.:|.|::..||:.     |.:..|...|:|  :...|: .||||..|.   ||:....|
Zfish   559 GLVGDLLSGVADMAVTSFSINSARSRVIDFTSPFFSTSLGILVRSKDTA---APIGAFMW----- 615

  Fly   347 PFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWWTCTSFGVC----TTFKLFISQSG 407
            |...::|..|.:.|...|..:.| |:               |. :.||:.    ...::|...|.
Zfish   616 PLHWSMWVGIFVALHITALFITL-YE---------------WN-SPFGMTPHGRNRIRVFSYSSA 663

  Fly   408 NSKAYSL--------------TVRVL--LFACFLNDLIITSIYGGGLASILTIPSMDEAADTVTR 456
            .:..|::              |.|.|  |:|.|.  |::.|.|...||:::......|....:..
Zfish   664 LNLCYAILFGRTVASKTPKCWTGRFLMNLWAIFC--LLVLSSYTANLAAVMVGEKTFEEVSGIHD 726

  Fly   457 LRFHRLQWAANSEAWVSAIR-ASDEALVKDILYNFHIY--------SDDELLRLAQDQHMRIGFT 512
            ::.|.......    ...:| :|.|..||......|.|        :.|.:..|..|......|.
Zfish   727 VKLHHPSLGFR----FGTVRESSAEDYVKKSFPEMHEYMRRFNKPTTPDGVSTLKTDPPQLDAFI 787

  Fly   513 VERLPFGHFAIGNYLGPQAIDQ----LVIMKDDIYFQYTVAFVPRLWPLLDKLNTLIYSWHSSGF 573
            :::      |:.:|  ..:||.    |.:.|......|.:. :|:..||...::..:..:.|.|:
Zfish   788 MDK------ALLDY--EVSIDADCKLLTVGKPFAIEGYGIG-LPQNSPLTRNVSEYVSRYKSDGY 843

  Fly   574 -----DKYWEYRVVADNLNLKIQQQVQETMTGTKDIGPVPLGMSNFAGFIIVWILGSAIATLTFL 633
                 ||:  |:||...   |....|.||:         .:|:.:|:|..::..:|.|.|.||.|
Zfish   844 MDMLHDKW--YKVVPCG---KRVFAVTETL---------QMGIQHFSGLFVLLCVGVAGALLTLL 894

  Fly   634 LE 635
            .|
Zfish   895 GE 896

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_Type_1	26..428	CDD:324556
grin3ba	XP_021323058.1	PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	69/334 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591694
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840