back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir41a and Gria1

DIOPT Version :9

Sequence 1:	NP_995744.4	Gene:	Ir41a / 2768714	FlyBaseID:	FBgn0040849	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_113796.1	Gene:	Gria1 / 50592	RGDID:	621531	Length:	907	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	94/470 - (20%)
Similarity:	174/470 - (37%)	Gaps:	84/470 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 NNLQGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFNCTIQ 270
            :::|.|..|:......||.::|.|.:   |..|        |...:|....:.....:....:.:
  Rat   402 SSVQNRTYIVTTILEDPYVMLKKNAN---QFEG--------NDRYEGYCVELAAEIAKHVGYSYR 455

  Fly   271 IDSSAANDWGKVYPNMSG-DGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPA 334
            ::..:...:|...|:... :|.:|.|:..:||:.:..:.........:|.|...:..||:.::..
  Rat   456 LEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520

  Fly   335 PLRLTSWYLP-LEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWWTCTS-----F 393
            |.:....... |:|....:|..|:......:..|.|..:.....:....:.||....||     |
  Rat   521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585

  Fly   394 GVCTT--FKL--FISQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSM----DEA 450
            |:..:  |.|  |:.|..:....||:.|::....:...|||.|.|...||:.||:..|    :.|
  Rat   586 GIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESA 650

  Fly   451 ADTV--------------TRLRFHRLQWAANSEAWV---SA-----IRASDEALVKDILYNFHIY 493
            .|..              |:..|.|.:.|...:.|.   ||     :|.::|.::: :..:...|
  Rat   651 EDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIR-VRKSKGKY 714

  Fly   494 SDDELLRLAQDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAFVPRLWPLL 558
            :  .||....::::.     :|.|.....:|..|..:.              |.:| .|:...|.
  Rat   715 A--YLLESTMNEYIE-----QRKPCDTMKVGGNLDSKG--------------YGIA-TPKGSALR 757

  Fly   559 DKLNTLIYSWHSSGFDKYWEYRVVADNLNLKIQQQVQETMTG---TKDIGPVPLGMSNFAGFIIV 620
            :.:|..:...:..|         :.|.|..|......|..:|   :|| ....|.:||.||...:
  Rat   758 NPVNLAVLKLNEQG---------LLDKLKNKWWYDKGECGSGGGDSKD-KTSALSLSNVAGVFYI 812

  Fly   621 WILGSAIATLTFLLE 635
            .|.|..:|.|..|:|
  Rat   813 LIGGLGLAMLVALIE 827

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.