Protein Alignment Ir41a and GluRIB

DIOPT Version :10

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 818
• Identity: 141/818 - (17%)
• Similarity: 238/818 - (29%)
• Gaps: 320/818 - (39%)

  Fly    29 NDKFEFQLLHKSDYISFVGINIKSFDDNGGHYIIDTGLK-KKELQNKHLFLDELVIKIIISIEVT 92
            :|::|      |:.|.|..|||..|      .|:||..: .:|..:....||. .:.:....|..
  Fly   269 DDRWE------SEIIEFGAINITGF------RIVDTNRRLVREFYDSWKRLDP-QMSVGAGRESI 320

  Fly    93 HCETFVVFDKDIDRFVNAFNKASVYSIWRSLHNKFVFAHIANESPESRNHFFEDQPNILFVVRDH 157
            ..:..:::|. :...|.||||                  |..:.|:...:..:.:...|.|.:..
  Fly   321 SAQAALMYDA-VFVLVEAFNK------------------ILRKKPDQFRNNVQRRSQTLMVAQAA 366

  Fly   158 SSASS------------------------------------FDIKTNKFVGRKAENPSQMILVDR 186
            :|.||                                    .|..|.|......|:..:   :.|
  Fly   367 ASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDK---ISR 428

  Fly   187 YLASEQRFQFGKSLFADKLNNLQGREVIIAGFDYPPYTVIKHNMSTNA---------QDMGVSG- 241
            ||...:.    :.|..|...|..||.|        .||:....|:.|:         .|.|:..
  Fly   429 YLRKVEI----EGLTGDIKFNDDGRRV--------NYTLHVVEMTVNSAMVKVAEWNDDAGLQPL 481

  Fly   242 -----------ESDFKNVYIDGT---ETRIVL----------------NFCEQ----------FN 266
                       |.:....||..|   |..|:|                .:|:.          .|
  Fly   482 NAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGIN 546

  Fly   267 CTIQI---------DSSAANDWGKVYPNMSGDGALGMLINRKADICIGAMYSWYEDYTYLDLSMY 322
            ..:::         .|||...|         ||.:|.|:.::|||.|.||....|....:|.|..
  Fly   547 YELRLVKDGNYGSEKSSAHGGW---------DGMVGELVRKEADIAIAAMTITAERERVIDFSKP 602

  Fly   323 LVRSGITCLVPAPLRLTSWYLP-LEPFKETLWAAILLCLCAEATGLVL----------------- 369
            .:..||:.::..|::.|..... :.|..:.:|.:::....  ...:||
  Fly   603 FMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYI--GVSIVLFFVSRFSPHEWRLVQQQ 665

  Fly   370 ----------AYKSEQALYVLPGY-------------REGWWTC--------------------- 390
                      |:..:.|....||.             ..|..|.
  Fly   666 PQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSS 730

  Fly   391 ----TSFGVCTTF----KLFISQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSM 447
                ..|.|..:|    ..|:.|..:....|::.|:...:.|...||:.|.|...||:.||:..|
  Fly   731 SAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERM 795

  Fly   448 --------DEAADTVTRLR----------FHRLQWAANSEAW-----------------VSAIRA 477
                    |.|..|..:..          |.|.|...:::.|                 :..:|.
  Fly   796 VTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRKHVFVPTYDEGIKRVRN 860

  Fly   478 S--DEALVKDILYNFHIYSDDELLRLAQDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKD 540
            |  ..||:.:...|.::.:.:..      ..|::|..::...||   |...||.
  Fly   861 SKGKYALLVESPKNEYVNAREPC------DTMKVGRNLDTKGFG---IATPLGS----------- 905

  Fly   541 DIYFQYTVAFVPRLWPLLDKLNTLIYSWHSSG-----FDKYWEYRVVADNLNLKIQQQVQETMTG 600
                           .|.|.:|..:.:...:|     .:|:|                .::....
  Fly   906 ---------------ALKDPINLAVLTLKENGELIKLRNKWW----------------YEKAECS 939

  Fly   601 TKDIGPV---PLGMSNFAGFIIVWILGSAIATLTFLLE 635
            |...|..   .|.:||.||...:.|.|..::....:||
  Fly   940 THKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILE 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..480	CDD:380603	48/257 (19%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	81/502 (16%)
		Lig_chan	630..966	CDD:459656	59/388 (15%)