Protein Alignment Ir41a and Nmdar1

DIOPT Version :10

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 142/705 - (20%)
• Similarity: 238/705 - (33%)
• Gaps: 223/705 - (31%)

  Fly    46 VGINIKSFDDNGGH-----YIIDTGLKKKELQNKHLFLDELVIKIIISIEVTHCETFVVFDKDI- 104
            :|:.::....:.||     |::.:.:|                      |:...||.....||.
  Fly   283 LGLQLEHAHSDKGHIRDSVYVLASAIK----------------------EMISNETIAEAPKDCG 325

  Fly   105 DRFVNAFNKASVYSIWRSLHNKFVFAHIANESPESRNHFFEDQPNILFV------VRDHSSAS-- 161
            |..||          |.|....|.:....|.:.|:....|:|..:.::.      :|:.....
  Fly   326 DSAVN----------WESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVV 380

  Fly   162 ---SFD---------IKTNKFV--GRKAENPSQMILVDRYL----ASEQRFQFGKSLFADKLNNL 208
               |:|         |..::.:  |::...| :.|::..:|    ..|:.|.:.:.:..|:..
  Fly   381 GKFSYDSMRAKMRMRINDSEIIWPGKQRRKP-EGIMIPTHLRLLTIEEKPFVYVRRMGDDEFR-- 442

  Fly   209 QGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFNCTIQIDS 273
                   ...|..|..:..::.:|       :.|...:...||     :::...::.|.|..:..
  Fly   443 -------CEPDERPCPLFNNSDAT-------ANEFCCRGYCID-----LLIELSKRINFTYDLAL 488

  Fly   274 SAANDWGK-VYPNMSG--------DGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGIT 329
            |....:|. :..|.:|        .|.:|.|:|.:||:.:..:....|...|::.|......|||
  Fly   489 SPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGIT 553

  Fly   330 CLVPAPLRLTSWYLPLEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWWTCTSFG 394
            .|...|.|.::....|:||..|||  ||:.:......||        ||:|..:       :.||
  Fly   554 ILEKKPSRSSTLVSFLQPFSNTLW--ILVMVSVHVVALV--------LYLLDRF-------SPFG 601

  Fly   395 VCTTFKLFISQSGNSKAYSLTVRV-LLFACFLND-----------------------LIITSIYG 435
               .|||..|.|...||.:|:..| ..:...||.                       :||.:.|.
  Fly   602 ---RFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYT 663

  Fly   436 GGLASILTI--PSMDEAADTVTRLR-------------------FHRLQWAANSEAWVSAIR-AS 478
            ..||:.|.:  |....:.....|||                   |.|....:|....:.|.. |:
  Fly   664 ANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYAT 728

  Fly   479 DEALVKDI----LYNFHIYSDDEL-LRLAQDQHMRIGFTVERLPFGH--FAIGNYLGPQAIDQLV 536
            .|..::|:    |..| |:....| ...::|..:   .|...| ||.  :.||...|.
  Fly   729 AEQAIQDVKKGKLMAF-IWDSSRLEYEASKDCEL---VTAGEL-FGRSGYGIGLQKGS------- 781

  Fly   537 IMKDDIYFQYTVAFVPRLWPLLDKLNTLIYSWHSSGF----DKYWEYR-VVADNLNLKIQQQVQE 596
                               |..|.:...|..:|.|||    ||.|.:. .|..|..|     .::
  Fly   782 -------------------PWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCEL-----FEK 822

  Fly   597 TMTGTKDIGPVPLGMSNFAGFIIVWILGSAIATLTFLLELSLTY----ILKQSNL 647
            |        |..||:.|.||..|  ::|..||....|:.:.:.|    :.||..|
  Fly   823 T--------PNTLGLKNMAGVFI--LVGVGIAGGVGLIIIEVIYKKHQVKKQKRL 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	24/153 (16%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	98/472 (21%)
		CaM_bdg_C0	854..882	CDD:402271	4/14 (29%)