Protein Alignment Ir41a and GluRIIB

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 623
• Identity: 106/623 - (17%)
• Similarity: 211/623 - (33%)
• Gaps: 199/623 - (31%)

  Fly    26 IFW----NDKFEFQLLH-KSDYI-----SFVGINIK-SFDDNGGHYIIDTGLKKKELQNKHLFLD 79
            |.|    |.:.:|.||. .||.:     :.:|.|:. ||:                    ||||.
  Fly   199 ILWKRINNAREKFVLLDCPSDILVDVINASIGYNMTGSFN--------------------HLFLT 243

  Fly    80 ELVIKI-----------IISIEVTHCETFV---------VFDKDIDRFVNAFNKASVYSIWRSLH 124
            .|...:           .:::......|:|         |||..:|...::.....||......:
  Fly   244 NLDTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFY 308

  Fly   125 NKFVFA------HIANESPESRNHFFEDQPNILFVVRDHSSASSFDIKTNKFVGRKAENP---SQ 180
            |..:..      :|.|.|  ....|::..|.:              ::..|.:..|...|   :|
  Fly   309 NALLEISQRPGFYIPNFS--CGRGFWQPGPRL--------------VEQMKQITPKMVKPPFKTQ 357

  Fly   181 MILVDRYLASEQRFQFGKSLF---ADKLNNLQGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSGE 242
            .:.::   |..||..|...::   .|::.::..:|..:..|:     .::.|.:...:...:..:
  Fly   358 RLQIN---ADGQREDFNLEVYNPIIDRVTHIWNKEFQLVDFE-----KLRENSTQALKQKRLQNK 414

  Fly   243 SDF------------------------KNVYIDGTE------TRIVLNFCEQFNCTIQIDSSAAN 277
            .||                        :.|:.:|.|      ..::....::.......:....|
  Fly   415 EDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDN 479

  Fly   278 DWGKVYPNM-SGDGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCL---VPAPLRL 338
            .:|....|. ..||.:..||:..|.|.|..:.......:.:|.::..::.||:.|   .|.|  .
  Fly   480 KYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPP--K 542

  Fly   339 TSWYLPLEPFKETLWAAILLCLCAEA-----TGLVLAYKSEQ-------------------ALYV 379
            ...|..|.|:...:|..:::.:...|     ||.:..|:.:|                   ||::
  Fly   543 ADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWL 607

  Fly   380 LPG--YREG----------------WWTCTSFGVCTTFKLFISQSGNSK--AYSLTVRVLLFACF 424
            :.|  ..:|                ||         .|.|.|||:..:|  |:..:.::......
  Fly   608 VLGSMLNQGCDLLPRGLPMRLLTAFWW---------IFALLISQTYIAKLAAFITSSKIAGDIGS 663

  Fly   425 LNDLI------ITSIYGGGLASILTIPSMDEAADTVTRLRFHRL------QWAANSEAWVSAIRA 477
            |:||:      ..:|.||.     |.....|:.||..|:.::::      .:..|:|..|..::.
  Fly   664 LHDLVDQNKVQFGTIRGGA-----TSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKL 723

  Fly   478 SDEA---LVKDILYNFHIYSDDELLRLAQ---DQHMRI 509
            |...   |::.....:::..:.||.::.:   ::|..|
  Fly   724 SKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGI 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	41/232 (18%)
		ANF_receptor	41..378	CDD:279440	39/217 (18%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	61/356 (17%)
		Lig_chan	555..822	CDD:278489	39/221 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462636
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930