Protein Alignment Ir41a and Grin2d

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 127/692 - (18%)
• Similarity: 226/692 - (32%)
• Gaps: 243/692 - (35%)

  Fly    16 GKYLNESTICIFWNDKFEFQLLHKSDYISFVGINIKSFDDNGGHYIIDTGLKKKELQNKHLFLDE 80
            |:.|:...:.|.|:::         ||         ||:::|  ::::..|
  Rat   354 GESLHRYFMNITWDNR---------DY---------SFNEDG--FLVNPSL-------------- 384

  Fly    81 LVIKIIISIEVTHCETFVVFDKDIDRFVNAFNKASV---YSIWRSLHNKFVFAHIANESPESRNH 142
                ::||:  |...|:.|        |.::.:.::   |.:| |.:.:|:      :..:...|
  Rat   385 ----VVISL--TRDRTWEV--------VGSWEQQTLRLKYPLW-SRYGRFL------QPVDDTQH 428

  Fly   143 F----FEDQPNILFVVRDHSSASSF--DIKTNKFVGRKAENPSQMILVDRYLASEQRFQFGKSLF 201
            .    .|::|.::....|..|.:..  .:.....:.|....|..        |.....:..|...
  Rat   429 LTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPD--------APRPEKRCCKGFC 485

  Fly   202 ADKLNNLQGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFN 266
            .|.|..|    ....||.|..|.|      ||    |..|:.      |||.
  Rat   486 IDILKRL----AHTIGFSYDLYLV------TN----GKHGKK------IDGV------------- 517

  Fly   267 CTIQIDSSAANDWGKVYPNMSGDGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCL 331
                        |         :|.:|.:..::||:.||::....|....:|.|:..|.:||:.:
  Rat   518 ------------W---------NGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVM 561

  Fly   332 V--------PAPLRLTSWYLP---LEPFKETLWAAI-LLCLCAEA-TGLVLAYKSEQAL--YVLP 381
            |        |:.....:|..|   .||:...:|..: ::||...| |..:..|.|....  .:..
  Rat   562 VARSNGTVSPSAFLAFAWLTPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLAT 626

  Fly   382 GYREGWWTCT-SFGVCTTFKLFISQS---GNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASIL 442
            |.|.|..|.| ...:...:.|..:.|   .|.:..:..:.||::|.|.  :|..:.|...||:.:
  Rat   627 GKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFA--VIFLASYTANLAAFM 689

  Fly   443 TIPSMDEAADTVTRL---RFHRLQWAANSEAWVSAIRASDEALVKDILYNFHIYSDDELLRLAQD 504
            .   .:|..|||:.|   :|.|.|.......:.:....|.|..::....:.|.|    ::|..|.
  Rat   690 I---QEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSY----MVRYNQP 747

  Fly   505 QHMRIGFTVERLPFGHF-------AIGNYLG---------------------------------- 528
               |:...:.:|..|..       |:.||:.
  Rat   748 ---RVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKR 809

  Fly   529 PQAIDQLVIMKDDIYFQYTVAFVPRLWPLLDKLNTLIYSWHSSGFDKYWEYRVVADNLNLKIQQQ 593
            |..:..|..:.||     .:..:.|||     |:.:.:                    |.||
  Rat   810 PIDLALLQFLGDD-----EIEMLERLW-----LSGICH--------------------NDKI--- 841

  Fly   594 VQETMTGTKDIGPVPLGMSNFAGFIIVWILGSAIATLTFLLE 635
              |.|:...||       .|.||...:.::...::.|.|..|
  Rat   842 --EVMSSKLDI-------DNMAGVFYMLLVAMGLSLLVFAWE 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	16/103 (16%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	94/514 (18%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350106
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930