Protein Alignment Ir41a and Grin3a

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001263284.1
• Gene: Grin3a / 242443
• MGIID: 1933206
• Length: 1135
• Species: Mus musculus
• Alignment Length: 627
• Identity: 124/627 - (19%)
• Similarity: 213/627 - (33%)
• Gaps: 188/627 - (29%)

  Fly   147 QPNILFVVRDHSSASSFDIKT-----NKFVGRKAENP-------SQMILVDRYLASEQRF----- 194
            ||.:..:   .|:.:..|:||     .:::.|...|.       |..:.....::||..|
Mouse   407 QPELALL---PSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNL 468

  Fly   195 ---QFGKSLFADKLNNLQGREVII-------------AGFDYP------PYTVIKHN--MSTNAQ 235
               ..||.::. :|.:.||..:::             ..|.:|      ..|:|:|.  .:....
Mouse   469 QYDPMGKPMWT-RLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVD 532

  Fly   236 DMGV--SG--------------ESDFKNVYIDGTETRIVLNFCEQFNCTIQIDSSAANDW----- 279
            |.|:  :|              :|.|.:::.......|....|....| |.:....|.|.
Mouse   533 DEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYC-IDLLEQLAEDMNFDFD 596

  Fly   280 ------GK--VYPNMSGDGALGMLINRKADIC-----IGAMYSWYEDYT--YLDLSM-YLVRSGI 328
                  ||  .:.|....|.:|.|::..|::.     |....|...|:|  :...|: .|||:..
Mouse   597 LYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRD 661

  Fly   329 TCLVPAPLRLTSWYLPLEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWWTCTSF 393
            |.   ||:....|     |...|:|..|.:.|...|..|.| |:.:....:.|..|
Mouse   662 TA---APIGAFMW-----PLHWTMWLGIFVALHITAIFLTL-YEWKSPFGMTPKGR--------- 708

  Fly   394 GVCTTFKLFISQSGNSKAYSL--------------TVRVL--LFACFLNDLIITSIYGGGLASIL 442
               ...|:|...|..:..|:|              |.|.|  |:|.|.  :...|.|...||:::
Mouse   709 ---NRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFC--MFCLSTYTANLAAVM 768

  Fly   443 TIPSMDEAADTVTRLRFHRLQWAANSEAWVSAIRASDEALVKDILYNFHIYSDDELLRLAQDQHM 507
            ....:.|....:...:.|.   .:....:.:...:|.|..|:......|             ::|
Mouse   769 VGEKIYEELSGIHDPKLHH---PSQGFRFGTVRESSAEDYVRQSFPEMH-------------EYM 817

  Fly   508 RIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAF---------------------V 551
            | .:.|...|.|...:.|  .|:.:|..::  |.....|.|:.                     :
Mouse   818 R-RYNVPATPDGVQYLKN--DPEKLDAFIM--DKALLDYEVSIDADCKLLTVGKPFAIEGYGIGL 877

  Fly   552 PRLWPLLDKLNTLIYSWHSSGF-----DKYWEYRVVADNLNLKIQQQVQETMTGTKDIGPVPLGM 611
            |...||...::.||..:.|.||     ||:  |:||...   |....|.||:         .:|:
Mouse   878 PPNSPLTSNISELISQYKSHGFMDVLHDKW--YKVVPCG---KRSFAVTETL---------QMGI 928

  Fly   612 SNFAGFIIVWILGSAIATLTFLLE-----LSLTYILKQSNLK 648
            .:|:|..::..:|..::.||.:.|     |.|..|..:|.|:
Mouse   929 KHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQ 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Grin3a	NP_001263284.1	PBP1_iGluR_NMDA_NR3	30..497	CDD:107372	17/93 (18%)
		PBP2_iGluR_NMDA_Nr3	512..908	CDD:270438	86/442 (19%)
		Lig_chan	676..942	CDD:278489	62/315 (20%)
		PPP2CB binding site. /evidence=ECO:0000250|UniProtKB:Q9R1M7	951..987		6/20 (30%)
		GIT1-binding. /evidence=ECO:0000250|UniProtKB:Q9R1M7	1082..1115

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840