Protein Alignment Ir41a and glr-3

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 794
• Identity: 141/794 - (17%)
• Similarity: 263/794 - (33%)
• Gaps: 285/794 - (35%)

  Fly     8 SLVLSAIVGKYLNESTICIFWNDKFEFQLLHKSDYI--------SFVG--INIKSFDDNGGHYII 62
            ||.::|.:.:...:..:.:|....   :||..:|.|        ||..  :.:|..||.|.
 Worm   136 SLAVAAFIKREKWKDVVVVFEEPD---ELLEITDMITAGHFDPDSFSSQLVRLKHGDDYGN---- 193

  Fly    63 DTGLKKKELQNKHLFLDELVIKIIISIE-----------VTHCET---FVVFDKDI--------- 104
                :.|.::||   ||...|.|.|.::           ::.|..   :||.|.|:
 Worm   194 ----ELKHIKNK---LDRYRIVINIPLQKALHFLEQAANMSMCGVLYHYVVMDMDLVTVDIDSIR 251

  Fly   105 ---DRFVNAF------------------NKASV----------YSIW--------RSLHNKFVFA 130
               |..:.:|                  :|:|:          .|||        ||:.:..::
 Worm   252 GIEDCNITSFGVHDVNSEYIEDIRQEIVHKSSIRLPKKGVPYTTSIWIDTLRLLIRSMKSIQIW- 315

  Fly   131 HIANESPESRNHFFEDQPNILFVVRDHSSASSFDIKTNKFVGRKAENPSQMILVD---------- 185
                           |:|..     ..|..|..|||...|     |||...|..|
 Worm   316 ---------------DEPRC-----GSSWKSGSDIKKRFF-----ENPLAGISGDLHWAPSGERS 355

  Fly   186 -----------------------RYLASEQRFQFGKSLFADKLNNLQGREVIIAGFDYPPYTVIK 227
                                   |.:||.:......|  ::|| .|:|:.:.|:.:...|:.:|.
 Worm   356 NYTLHVYRRTLSFQKFAEWSSRTRRIASSEAVVIANS--SEKL-TLEGKHLKISVYLEAPFVMIT 417

  Fly   228 HNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFNCTIQIDSSAANDWGKVYPNMSGDGAL 292
            .|.|             ::...||     ::.........|..|.....|.:|....|....|.:
 Worm   418 SNGS-------------YEGYCID-----LLHKIANILKFTYTIQKVRDNAYGSKESNGKWSGMV 464

  Fly   293 GMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPAP-LRLTSWYLPLEPFKETLW--- 353
            |.|....||:.:.::...|.....:|.::..:..||:.|...| :|.:.|:..::|....:|
 Worm   465 GELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDSDWFKFMDPLSTQVWIMT 529

  Fly   354 ------AAILLCLCAEATGLVLAYKSEQALYVLP-----GYREGWWTCTSFGVCTTFKLFISQSG 407
                  .::.:.:.|:.:......:.|......|     ..|..:|    |.||:     :.|.|
 Worm   530 FASYFVVSVAIWIIAKISPYEQFERDEDNGQYKPVDNQFSLRNSFW----FTVCS-----LMQQG 585

  Fly   408 NSKA-YSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSMD---EAADTV---TRLRFHRL--- 462
            :... .:.:.|:|....:...||:.|.|...||::||...|:   |.||.:   |::::..|
 Worm   586 SELCPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAAQTKIKYGTLGRG 650

  Fly   463 ----------------QW----------AANSEAWVSAIRASDEA-LVKDILYNFHIYSDDELLR 500
                            .|          ..:|:..::.:::||.| |::..:..:.:..|.||
 Worm   651 STMSFFNESKIETYERMWQLMSSSPGLFVQSSKEGIARVKSSDYAYLMESSMLEYAVERDCEL-- 713

  Fly   501 LAQDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAFVPRLWPLLDKLNTLI 565
                  |:||..:::..:|   ||                          :|:..|..:.::|.|
 Worm   714 ------MQIGGLIDQKGYG---IG--------------------------LPKGSPYRELISTAI 743

  Fly   566 YSWHSSG-----FDKYWEYRVVADNLNLKIQQQVQETMTGTKDIGPVPLGMSNFAGFIIVWILGS 625
            .......     .:|:|:.:.|.      .:|..::.....:.||          |..|:.::|.
 Worm   744 LRLQEKTELTELKEKWWKDKSVV------CEQPKRKDQDDGESIG----------GIFIILVVGL 792

  Fly   626 AIATLTFLLELSLT 639
            .:..:..:.||..|
 Worm   793 VLTAVLVIFELITT 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	52/288 (18%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	73/423 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910