Protein Alignment Ir41a and gria2a

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_005170953.1
• Gene: gria2a / 170450
• ZFINID: ZDB-GENE-020125-3
• Length: 893
• Species: Danio rerio
• Alignment Length: 723
• Identity: 129/723 - (17%)
• Similarity: 228/723 - (31%)
• Gaps: 250/723 - (34%)

  Fly    46 VGINIKSFDDNGGHYII------DTGLKKKELQNKHLFLDELVIKIIISIEVTHCETFVVFDKDI 104
            :|.::|     |.||||      |..|.|                  |.....:...|.:.|.|
Zfish   221 IGRHVK-----GYHYIIANFGFVDGDLSK------------------IQYGGANVSGFQIVDFD- 261

  Fly   105 DRFVNAFNKASVYSIWRSLHNKFVFAHIANESP--ESRNHFFEDQPNILFVVRDHSSASSFD--- 164
            |..|..|::.     |.:|..|        |.|  :||             :| ::||.::|
Zfish   262 DPLVAKFDQR-----WEALEEK--------EYPGADSR-------------IR-YTSALTYDAVQ 299

  Fly   165 IKTNKF---------VGRKAE------NPS-------------QMILVDRYLASEQRFQFGK--- 198
            :.|..|         :.|:..      ||:             :.:.||....:.|..|:|:
Zfish   300 VMTEAFRFLHKQRIDISRRGNNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGRRVN 364

  Fly   199 ------------------------------SLFADKLNNLQGREVIIAGFDYPPYTVIKHN---M 230
                                          .||.:....::.:.||:......||.::|.|   .
Zfish   365 YTVNVMELKNSGPVKIGYWNEMDKMAVTKSDLFPNDTMGMENKTVIVTTILEAPYVMLKKNAELF 429

  Fly   231 STNAQDMG--------VSGESDFK---NVYIDG------TETRIVLNFCEQFNCTIQIDSSAAND 278
            :.|.:..|        ::....||   .:..||      .||:|
Zfish   430 TDNERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGARDAETKI--------------------- 473

  Fly   279 WGKVYPNMSGDGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPAPLRLTSWYL 343
            |         :|.:|.|:..||||.:..:.........:|.|...:..||:.::..|.:......
Zfish   474 W---------NGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529

  Fly   344 P-LEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWW----TCTSFGVCTT--FKL 401
            . |:|....:|..|:......:..|.|..:.....:....:.:|..    :...||:..:  |.|
Zfish   530 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGQLGPSESTNEFGIFNSLWFSL 594

  Fly   402 --FISQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSM----DEAADTV------ 454
              |:.|..:....||:.|::....:...|||.|.|...||:.||:..|    :.|.|..
Zfish   595 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 659

  Fly   455 --------TRLRFHRLQWAANSEAWVSAIRASDEALVKDILYNF---------HIYSDDELLRLA 502
                    |:..|.|.:.|...:.|.....|.....||:.:...         :.|    ||...
Zfish   660 YGTLDAGSTKEFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLRVRKSKGKYAY----LLEST 720

  Fly   503 QDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAFVPRLWPLLDKLNTLIYS 567
            .::::.     :|.|.....:|..|..:.              |.:| .|:...|.:.:|..:..
Zfish   721 MNEYIE-----QRKPCDTMKVGGNLDSKG--------------YGIA-TPKGSALRNAVNLAVLK 765

  Fly   568 WHSSGF-----DKYWEYRVVADNLNLKIQQQVQETMTGTKDIGPVPLGMSNFAGFIIVWILGSAI 627
            .:..|.     :|:|..:....:...:.:::..            .|.:||.||...:.:.|..:
Zfish   766 LNEQGLLDKLKNKWWYDKGECGSGGGESKEKTS------------ALSLSNVAGVFYILVGGLGL 818

  Fly   628 ATLTFLLE 635
            |.|..|:|
Zfish   819 AMLVALVE 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
gria2a	XP_005170953.1	Periplasmic_Binding_Protein_Type_1	23..391	CDD:299141	38/220 (17%)
		ANF_receptor	51..373	CDD:279440	38/202 (19%)
		PBP2_iGluR_AMPA	406..783	CDD:270433	79/430 (18%)
		Lig_chan	538..816	CDD:278489	54/313 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591734
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840