Protein Alignment Ir41a and Grin2c

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 584
• Identity: 111/584 - (19%)
• Similarity: 203/584 - (34%)
• Gaps: 130/584 - (22%)

  Fly   129 FAHIANESPESRNHFFED-----QPNILFVVRDHSSASSFDIKTNKFVGRKAENPSQM--ILVDR 186
            :.|:.|.:.|.|:..|..     ||.::.:..:..       :..:.|||.......|  .:..|
Mouse   394 YRHLLNVTWEGRDFSFSPGGYLVQPTMVVIALNRH-------RLWEMVGRWDHGVLYMKYPVWPR 451

  Fly   187 YLASEQRFQFGKSLFADKLNNLQGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSG--------ES 243
            |..|.|..             :..|.:.:|..:..|:.:::      :.|.|..|        ..
Mouse   452 YSTSLQPV-------------VDSRHLTVATLEERPFVIVE------SPDPGTGGCVPNTVPCRR 497

  Fly   244 DFKNVYIDGTETRIVLNFCEQFNCTIQIDSSAAN-----------DWGKVYPNMSG--DGALGML 295
            ...:.:..|..|......|:.| | |.|....|.           ..||....:.|  :|.:|.:
Mouse   498 QSNHTFSSGDITPYTKLCCKGF-C-IDILKKLAKVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEV 560

  Fly   296 INRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPAPLRLTSWYLPLEPFKETLWAAI-LLC 359
            ..::||:.||::....|....:|.|:..|.:||:.:|.......|....|||:...:|..: ::|
Mouse   561 YYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMC 625

  Fly   360 LCAEA-TGLVLAYKSEQAL--YVLPGYREGWWTCT-SFGVCTTFKLFISQS---GNSKAYSLTVR 417
            |...| |..:..|.|..:.  .:..|.:.|..:.| ...|...:.|..:.|   .|.:..:..:.
Mouse   626 LTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIM 690

  Fly   418 VLLFACFLNDLIITSIYGGGLASILTIPSMDEAADTVTRL---RFHRLQWAANSEAWVSAIRASD 479
            ||::|.|.  :|..:.|...||:.:.   .::..|||:.|   :|.|.|.......:.:....|.
Mouse   691 VLVWAFFA--VIFLASYTANLAAFMI---QEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGST 750

  Fly   480 EALVKDILYNFHIYSDDELLRLAQDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIM----KD 540
            |..::....:.|.:......|..:|       .:..|..|...:...|.....|..|:.    ||
Mouse   751 ERNIRSNYRDMHTHMVKFNQRSVED-------ALTSLKMGARHVSRKLDAFIYDAAVLNYMAGKD 808

  Fly   541 DIYFQYTVAFVPRLWPLLDKLNTL----IYSWHSSGF----DKYWEYRV-------VADNLNLKI 590
            :..                ||.|:    :::....|.    |.:|:..:       :.|....|:
Mouse   809 EGC----------------KLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKL 857

  Fly   591 Q---------QQVQETMTGTKDIGPVPLGMSNFAGFIIVWILGSAIATLTFLLELSLTYILKQS 645
            :         .:..|.|:...||       .|.||...:.::...:|.|.|..|..:.:.|:.|
Mouse   858 ETVWLSGICHNEKNEVMSSKLDI-------DNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHS 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	11/58 (19%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	83/441 (19%)
		NMDAR2_C	905..>980	CDD:371139	2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930