Protein Alignment Ir41a and Grin2b

DIOPT Version :9

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001350679.1
• Gene: Grin2b / 14812
• MGIID: 95821
• Length: 1482
• Species: Mus musculus
• Alignment Length: 598
• Identity: 117/598 - (19%)
• Similarity: 220/598 - (36%)
• Gaps: 151/598 - (25%)

  Fly   113 KASVYSIWRSLHNKFVF------AHIANESPESRN-HFFED----QPNILFVVRDHSSASSFDIK 166
            |:|.|    :.|.|.::      .::.|.:.|.|| .|.||    .|.::.::.:         |
Mouse   318 KSSCY----NTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLN---------K 369

  Fly   167 TNKF--VGRKAENPSQMILVDRYLASEQRFQFGKSLFADKLNNLQGRE---VIIAGFDYPPYTVI 226
            ..|:  ||:..:...||    :|....:.....:....|.|:.:...|   ||:...|....|.:
Mouse   370 ERKWERVGKWKDKSLQM----KYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCM 430

  Fly   227 KHNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFNCTIQIDSSAANDW-------GKVYP 284
            ::.:....:.:. ..::|.:..||    .:....||  .:...:|..|....:       ||...
Mouse   431 RNTVPCQKRIIS-ENKTDEEPGYI----KKCCKGFC--IDILKKISKSVKFTYDLYLVTNGKHGK 488

  Fly   285 NMSG--DGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPAPLRLTSWYLPLEP 347
            .::|  :|.:|.::.::|.:.:|::....|....:|.|:..:.:||:.:|.......|....|||
Mouse   489 KINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEP 553

  Fly   348 FKETLWAAILLCLCAEATGLVLAYKSEQALYVLP-GYREGWWTCTSFG-------------VCTT 398
            |...:|..:.:.|...:...|..::     |..| ||..    |.:.|             :...
Mouse   554 FSADVWVMMFVMLLIVSAVAVFVFE-----YFSPVGYNR----CLADGREPGGPSFTIGKAIWLL 609

  Fly   399 FKLFISQS---GNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSMDEAADTVTRL--- 457
            :.|..:.|   .|.|..:..:.|.::|.|.  :|..:.|...||:.:.   .:|..|.|:.|
Mouse   610 WGLVFNNSVPVQNPKGTTSKIMVSVWAFFA--VIFLASYTANLAAFMI---QEEYVDQVSGLSDK 669

  Fly   458 RFHRLQWAANSEAWVSAIRASDEALVKDILYNFHIYS--------DDELLRLAQDQHMRIG---- 510
            :|.|....:....:.:....|.|..:::.....|.|.        ||.||.|      :.|
Mouse   670 KFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSL------KTGKLDA 728

  Fly   511 FTVERLPFGHFAIGNYL-GPQAIDQLVIMKDDIYFQYTVAFVPRLWPLLDKLNTLIYSWHSSGF- 573
            |..:.      |:.||: |.....:||.:.....|.                        |:|:
Mouse   729 FIYDA------AVLNYMAGRDEGCKLVTIGSGKVFA------------------------STGYG 763

  Fly   574 -----DKYWEYRVVADNLNLKIQQQVQET----MTG-----TKDIGPVPLGMSNFAGFIIVWILG 624
                 |..|:.:|....|.|....:::|.    :||     ..::....|.:.|.||  :.::||
Mouse   764 IAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAG--VFYMLG 826

  Fly   625 SAIA--TLTFLLE 635
            :|:|  .:||:.|
Mouse   827 AAMALSLITFICE 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
Grin2b	NP_001350679.1	PBP1_iGluR_NMDA_NR2	33..388	CDD:380601	19/86 (22%)
		PBP2_iGluR_NMDA_Nr2	403..803	CDD:270436	86/456 (19%)
		NMDAR2_C	840..1482	CDD:402274	117/598 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846448
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840