Protein Alignment Ir41a and gria4

DIOPT Version :10

• Sequence 1: NP_995744.4
• Gene: Ir41a / 2768714
• FlyBaseID: FBgn0040849
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_031751480.1
• Gene: gria4 / 100125052
• XenbaseID: XB-GENE-5838893
• Length: 902
• Species: Xenopus tropicalis
• Alignment Length: 784
• Identity: 145/784 - (18%)
• Similarity: 244/784 - (31%)
• Gaps: 272/784 - (34%)

  Fly    10 VLSAIVGKY----LNESTICI-FWNDKFEFQLLHKSD---------------------YISFVGI 48
            :|.||:.|.    ...|.||: .:||....:||...|                     .|..||.
 Frog   166 ILQAIMEKAGQNGWQVSAICVENFNDASYRRLLEDLDRRQENKFVIDCEVERLQNILEQIVSVGK 230

  Fly    49 NIKSFDDNGGHYII-DTGLKKKELQNKHLFLDELVIKIIISIEVTHCETFVVFDKDIDRFVNA-- 110
            ::|     |.|||| :.|.|                                 |..:|||::.
 Frog   231 HVK-----GYHYIIANLGFK---------------------------------DISLDRFMHGGA 257

  Fly   111 ---------FNKASVYSI---WRSLHNKFVFAHIANESPESRNHFFEDQPNILFVVRDHSSASSF 163
                     ||...|..:   |::|..:   .:..:|||..                 ::||.::
 Frog   258 NVTGFQLVDFNTPIVTELMQRWKTLDQR---EYPGSESPPK-----------------YTSALTY 302

  Fly   164 D-----------IKTNKF-------VGRKAENPS----QMILVDRYLASEQRFQ----------F 196
            |           ::..|.       .|....||:    |.|.::|.| .:.|.|          :
 Frog   303 DGVLVMAEAFRILRRQKIDLSRRGNAGDCLANPAAPWGQGIDMERTL-KQVRIQGLTGNIQFDHY 366

  Fly   197 GKSL----------------------------------FADKLNNLQGREVIIAGFDYPPYTVIK 227
            |:.:                                  |.:..:.::.|.||:......||.:.|
 Frog   367 GRRVNYTMDVLELKSNGLRKIGYWNDMDKLVLLQHEPAFKNDSSGIENRTVIVTTILEAPYVMYK 431

  Fly   228 HNMSTNAQDMGVSGESDFKNVYIDGTETRIVLNFCEQFNCTIQIDS--SAANDWGKVYPNMSGDG 290
            .|...      :.|...|:...:| ....|..:...::...|..|.  .|.:...|::     :|
 Frog   432 KNHEL------LEGNDKFEGYCVD-LAYEIAKHIGIKYKIAIVPDGKYGARDSETKIW-----NG 484

  Fly   291 ALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVPAPLRLTSWYLP-LEPFKETLWA 354
            .:|.|:..||:|.:..:.........:|.|...:..||:.::..|.:....... |:|....:|.
 Frog   485 MVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 549

  Fly   355 AILLCLCAEATGLVLAYKSEQALYVLPGYREGWWT--------------CTSFGVCTT--FKL-- 401
            .|:....  ...:||...|..:.|       .|.|              ...||:..:  |.|
 Frog   550 CIVFAYI--GVSVVLFLVSRFSPY-------EWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGA 605

  Fly   402 FISQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSM----DEAADTV-------- 454
            |:.|..:....||:.|::....:...|||.|.|...||:.||:..|    :.|.|..
 Frog   606 FMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670

  Fly   455 ------TRLRFHRLQWAANSEAWVSAIRASDEALVKDILYNFHIYSDDELLRLAQDQHMRIGFTV 513
                  |:..|.|.:.|...:.|.....|......|.        :.:.:.|:.:.:. :..|.:
 Frog   671 TLDAGSTKEFFKRSKIAVYEKMWTYMKSAEPSVFTKT--------TAEGVARVRKSKG-KFAFLL 726

  Fly   514 E---------RLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAFVPRLWPLLDKLNTLIYSWH 569
            |         |.|.....:|..|..:.              |.|| .|:...|.:.:|..:...:
 Frog   727 ESTMNEYIEQRKPCDTMKVGGNLDSKG--------------YGVA-TPKHSQLRNAVNLAVLKLN 776

  Fly   570 SSGFDKYWEYRVVADNLNLKIQQQVQETMTG---TKDIGPVPLGMSNFAGFIIVWILGSAIATLT 631
            ..|         :.|.|..|......|..:|   :|| ....|.:||.||...:.:.|..:|.|.
 Frog   777 EQG---------LLDKLKNKWWYDKGECGSGGGDSKD-KTSALSLSNVAGVFYILVGGLGLAMLV 831

  Fly   632 FLLE 635
            .|:|
 Frog   832 ALIE 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir41a	NP_995744.4	None
gria4	XP_031751480.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	49/292 (17%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	81/434 (19%)