DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCAP-R and Ptger2

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_112350.1	Gene:	Ptger2 / 81752	RGDID:	620020	Length:	357	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	81/359 - (22%)
Similarity:	143/359 - (39%)	Gaps:	52/359 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 NSTSSDPGEFDNLNS-FYFYETEQFAVLWILFTVIVLGNSAVLFVMFI-----------NKNRKS 156
            :::.:|....:|..| .|....|..|:..::||..||||...|.::..           ::...|
  Rat     2 DNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAGSRTSIS 66

  Fly   157 RMNYFIKQLALADL---CVGLLNVLTDIIWRIT-ISWRAGNLACKAIRFSQVCVTYSSTYVLVAM 217
            ..:..:.:|.|.||   |:....||.......| ::....:.||....|:....:.::..:|.||
  Rat    67 LFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFFSLATMLMLFAM 131

  Fly   218 SIDRYDAITHPMNFSKSWKRARHL--VAGAWLISALF-SLPILVLYEEKLIQGHP--QCWIELGS 277
            :::||.||.||..:.:...|...|  :...:.:|.|| |||:|...|  .:|..|  .|:|:.|.
  Rat   132 ALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGE--YVQYCPGTWCFIQHGR 194

  Fly   278 PIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAGFGAAPARRASSRGIIPR 342
            ....|:|.:::...:.|:....||....:|...:.:|.|      |.|...:..|...||....|
  Rat   195 TAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRS------RCGLSGSSLRGPGSRRRGER 253

  Fly   343 AK--------VKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSA 399
            ..        :....||:|    |.:|..|:.||..:..... ...:.::....|:.    :||.
  Rat   254 TSMAEETDHLILLAIMTIT----FAVCSLPFTIFAYMDETSS-RKEKWDLRALRFLS----VNSI 309

  Fly   400 ANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYR 433
            .:|.::.:....|.|.:      :...||..|.|
  Rat   310 IDPWVFVILRPPVLRLM------RSVLCCRTSLR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	73/319 (23%)
		TM helix 1	126..150	CDD:320325	8/23 (35%)
		TM helix 2	159..182	CDD:320325	7/25 (28%)
		TM helix 3	197..219	CDD:320325	4/21 (19%)
		TM helix 4	240..256	CDD:320325	6/18 (33%)
		TM helix 5	282..305	CDD:320325	5/22 (23%)
		TM helix 6	348..370	CDD:320325	8/21 (38%)
		TM helix 7	384..409	CDD:320325	4/24 (17%)
Ptger2	NP_112350.1	7tm_1	39..314	CDD:278431	65/291 (22%)
Ptger2	NP_112350.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	235..255		5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000