DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCAP-R and oxtrb

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001186298.1	Gene:	oxtrb / 796298	ZFINID:	ZDB-GENE-110805-1	Length:	382	Species:	Danio rerio

Alignment Length:	356	Identity:	117/356 - (32%)
Similarity:	183/356 - (51%)	Gaps:	32/356 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 QFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWR 190
            :..||.::..:.:.||..||..:..:|:.:|||.||:|.|::|||.|.:..||..:||.||..:.
Zfish    46 EVTVLVLILLLALAGNLCVLVAIQTSKHGQSRMYYFMKHLSIADLVVAVFQVLPQLIWDITFRFY 110

  Fly   191 AGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSLP 255
            ..:..|:.:::.||...::|||:||.|||||..||..|:. |...::.|..|..:|:||.|||||
Zfish   111 GPDFLCRLVKYLQVVGMFASTYMLVLMSIDRCLAIWQPLR-SLRRRKDRFYVLASWIISLLFSLP 174

  Fly   256 ILVLYEEKLI-QGHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIW------- 312
            .:.::..:.: .|...||.:...|...:.|::.:|.|::.||..|:|.||.:|...||
Zfish   175 QVYIFSLREVGDGVFDCWGDFVQPWGAKAYVTWISLTIYIIPVAILSVCYGLISYKIWQNFRLKT 239

  Fly   313 AKGSIFVPTERAGFGAAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQI 377
            .:......|.|...||| ..|.||..:|.:||::|||||..||..:||||:|:....:...:..:
Zfish   240 RRDQCLSLTPRPTKGAA-LSRVSSVKLISKAKIRTVKMTFVIVMAYIICWTPFFFVQMWSAWDPM 303

  Fly   378 -PHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFT---CCCKSYRNNSQQ 438
             |.......||..   ||.|||..||.||..|:..:||.|.:    :..|   |.||.:..|..
Zfish   304 APREAMAFIIAML---LASLNSCCNPWIYMFFAGHLFRDLMQ----RCLTVSHCGCKRHWRNKN- 360

  Fly   439 NRCHTVGRRLHNSCDSMRTLTTSLTVSRRST 469
                      |:...:||:.::..:|::.||
Zfish   361 ----------HSGTGAMRSSSSQKSVTQSST 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	105/298 (35%)
		TM helix 1	126..150	CDD:320325	6/23 (26%)
		TM helix 2	159..182	CDD:320325	10/22 (45%)
		TM helix 3	197..219	CDD:320325	8/21 (38%)
		TM helix 4	240..256	CDD:320325	8/15 (53%)
		TM helix 5	282..305	CDD:320325	8/22 (36%)
		TM helix 6	348..370	CDD:320325	11/21 (52%)
		TM helix 7	384..409	CDD:320325	11/24 (46%)
oxtrb	NP_001186298.1	7tm_1	60..329	CDD:278431	98/273 (36%)
oxtrb	NP_001186298.1	7tm_4	61..>172	CDD:304433	44/111 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I4004
OMA	1	1.010	-	-		QHG45270
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24293
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.060