DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCAP-R and PTGFR

DIOPT Version :9

Sequence 1:NP_001368957.1 Gene:CCAP-R / 2768688 FlyBaseID:FBgn0039396 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_000950.1 Gene:PTGFR / 5737 HGNCID:9600 Length:359 Species:Homo sapiens


Alignment Length:326 Identity:75/326 - (23%)
Similarity:129/326 - (39%) Gaps:57/326 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 FAVLWILFTVIVLGNS---AVLFVMFINKNRKSRMNYFI--KQLALADLCVGLLN-VLTDIIWRI 185
            |:|  |..||.:|.||   |:|...:....:||:.::.:  ..|.:.|....|:| .:...::..
Human    32 FSV--IFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYAS 94

  Fly   186 TISWRAGNLACKAIRFSQ---------VCVTYSSTYVLV---AMSIDRYDAITHPMNFSK--SWK 236
            ...|         |||.|         :|:.:|....|:   .|:|:|...:|.|:..|.  :.|
Human    95 DKEW---------IRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSK 150

  Fly   237 RARHLVAGAWLISALFS-LPILVLYEEKLIQGHPQCWIELGSPIAWQVYMSLVSATLFAIPALII 300
            ..:.:::|..|.:...: ||||...:.|:......|:........|:....|:..:...:.||.:
Human   151 HVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGV 215

  Fly   301 S-ACYAIIVKTIWAKGSIFVPTERAGFGAAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSP 364
            | .|.||...|:.          |..|.:...|:..|.      .::.|...|.|:.|..|||||
Human   216 SLLCNAITGITLL----------RVKFKSQQHRQGRSH------HLEMVIQLLAIMCVSCICWSP 264

  Fly   365 YII-FDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCC 428
            ::: ...:.:.|.  ||........|...:|..|...:|.:|.|....|.:.|     :|..:.|
Human   265 FLVTMANIGINGN--HSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNL-----YKLASQC 322

  Fly   429 C 429
            |
Human   323 C 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCAP-RNP_001368957.1 7tmA_NPSR 124..416 CDD:320325 71/311 (23%)
TM helix 1 126..150 CDD:320325 10/25 (40%)
TM helix 2 159..182 CDD:320325 4/25 (16%)
TM helix 3 197..219 CDD:320325 8/33 (24%)
TM helix 4 240..256 CDD:320325 3/16 (19%)
TM helix 5 282..305 CDD:320325 5/23 (22%)
TM helix 6 348..370 CDD:320325 9/22 (41%)
TM helix 7 384..409 CDD:320325 6/24 (25%)
PTGFRNP_000950.1 7tmA_FP 27..316 CDD:320273 72/317 (23%)
TM helix 1 28..54 CDD:320273 10/23 (43%)
TM helix 2 66..92 CDD:320273 4/25 (16%)
TM helix 3 108..138 CDD:320273 6/29 (21%)
TM helix 4 150..172 CDD:320273 5/21 (24%)
TM helix 5 197..226 CDD:320273 7/28 (25%)
TM helix 6 242..272 CDD:320273 10/35 (29%)
TM helix 7 283..308 CDD:320273 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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