DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCAP-R and PTGDR

DIOPT Version :9

Sequence 1:NP_001368957.1 Gene:CCAP-R / 2768688 FlyBaseID:FBgn0039396 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_000944.1 Gene:PTGDR / 5729 HGNCID:9591 Length:359 Species:Homo sapiens


Alignment Length:372 Identity:79/372 - (21%)
Similarity:142/372 - (38%) Gaps:73/372 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 NSTSSDPGEFDNLNSFYFYETEQFAVL-WILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQ--- 164
            |:||.:.|     ||         ||: .:||:..:|||...|.::     .:|.:.:..::   
Human    10 NTTSVEKG-----NS---------AVMGGVLFSTGLLGNLLALGLL-----ARSGLGWCSRRPLR 55

  Fly   165 ---LALADLCVGLLNVLTDIIWRITIS-----------------WRAGNLACKAIRFSQVCVTYS 209
               .....|..||  .:||::.:..:|                 ....|..|:|..|.......|
Human    56 PLPSVFYMLVCGL--TVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLS 118

  Fly   210 STYVLVAMSIDRYDAITHPMNFSKSWKRARHLV--AGAWL--ISALFSLPILVL---YEEKLIQG 267
            ||..|:||:::.:.::.||..:      .||:.  .||.:  :.:.|||....|   ...|.:|.
Human   119 STLQLLAMALECWLSLGHPFFY------RRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQY 177

  Fly   268 HPQCWI------ELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAGF 326
            .|..|.      |.|| ::...| |::.::|.|:..|....|....::.::|.........|:..
Human   178 CPGTWCFIQMVHEEGS-LSVLGY-SVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT 240

  Fly   327 GAAPARRASSRGIIPR--AKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATF 389
            ......||..|...|:  .::..:.:...:..:|.:|..|.|.......|..:.........|..
Human   241 RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAED 305

  Fly   390 IQSLAPLN--SAANPLIYCLFSSQVFRTLSR---FPPFKWFTCCCKS 431
            :::|..|:  |..:|.|:.:|.|.|||....   ..|.::.:.|..|
Human   306 LRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNS 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCAP-RNP_001368957.1 7tmA_NPSR 124..416 CDD:320325 70/332 (21%)
TM helix 1 126..150 CDD:320325 8/24 (33%)
TM helix 2 159..182 CDD:320325 5/28 (18%)
TM helix 3 197..219 CDD:320325 8/21 (38%)
TM helix 4 240..256 CDD:320325 6/19 (32%)
TM helix 5 282..305 CDD:320325 6/22 (27%)
TM helix 6 348..370 CDD:320325 4/21 (19%)
TM helix 7 384..409 CDD:320325 6/26 (23%)
PTGDRNP_000944.1 7tmA_PGD2 17..335 CDD:320268 73/346 (21%)
TM helix 1 18..44 CDD:320268 10/39 (26%)
TM helix 2 61..87 CDD:320268 6/27 (22%)
TM helix 3 105..135 CDD:320268 9/29 (31%)
TM helix 4 147..169 CDD:320268 6/21 (29%)
TM helix 5 195..224 CDD:320268 6/29 (21%)
TM helix 6 258..288 CDD:320268 4/29 (14%)
TM helix 7 302..327 CDD:320268 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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