DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCAP-R and Avpr1b

DIOPT Version :9

Sequence 1:NP_001368957.1 Gene:CCAP-R / 2768688 FlyBaseID:FBgn0039396 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_036054.1 Gene:Avpr1b / 26361 MGIID:1347010 Length:421 Species:Mus musculus


Alignment Length:408 Identity:128/408 - (31%)
Similarity:214/408 - (52%) Gaps:62/408 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 DLETGGNSTSSDPGEF--DNLNSFYFYETEQFA--VLWILFTVIVL---GNSAVLFVMFINKNRK 155
            |.|....:|.|..|..  .|..:.:....|:.|  .:.||.||:||   ||.|||.::.:..:::
Mouse     2 DSEPSWTATPSPGGTLFVPNTTTPWLGRDEELAKVEIGILATVLVLATGGNLAVLLILGLQGHKR 66

  Fly   156 SRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSID 220
            |||:.|:..|||.||.|.|..||..::|.||..::..:|.|:|:::.||...::|||:|:||::|
Mouse    67 SRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQGSDLLCRAVKYLQVLSMFASTYMLLAMTLD 131

  Fly   221 RYDAITHPMNFSKSWKRARH-LVAGAWLISALFSLPILVLYE-EKLIQGHP--QCWIELGSPIAW 281
            ||.|:.||:...:...::.: |:|..||::|:.|||.:.::. .::|||..  .||.:.  ..:|
Mouse   132 RYLAVCHPLRSLQQPSQSTYPLIAAPWLLAAILSLPQVFIFSLREVIQGSGVLDCWADF--YFSW 194

  Fly   282 --QVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPT-----ERAGF--GAAPARRASSR 337
              :.|::..:..:|.:|.::::|||.:|...|:.  ::.|.|     ||.|:  .::.|..|::|
Mouse   195 GPRAYITWTTMAIFVLPVVVLTACYGLICHEIYK--NLKVKTQAGREERRGWPKSSSSAAAAATR 257

  Fly   338 GI---------IPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQ-IPH-SQTNIAIATFIQ 391
            |:         |.|||::|||||..||..:|.||:|:....:..|:.: .|: ..||:|. |...
Mouse   258 GLPSRVSSISTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDENAPNEDSTNVAF-TISM 321

  Fly   392 SLAPLNSAANPLIYCLFSSQVF-RTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSM 455
            .|..|:|..||.||..|:|.:. |:||.       ..||:..:            .|:|      
Mouse   322 LLGNLSSCCNPWIYMGFNSHLLPRSLSH-------RACCRGSK------------PRVH------ 361

  Fly   456 RTLTTSLTVSRRSTNKTN 473
            |.|:.|...|||:|..|:
Mouse   362 RQLSNSSLASRRTTLLTH 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCAP-RNP_001368957.1 7tmA_NPSR 124..416 CDD:320325 108/321 (34%)
TM helix 1 126..150 CDD:320325 12/28 (43%)
TM helix 2 159..182 CDD:320325 10/22 (45%)
TM helix 3 197..219 CDD:320325 9/21 (43%)
TM helix 4 240..256 CDD:320325 7/16 (44%)
TM helix 5 282..305 CDD:320325 5/22 (23%)
TM helix 6 348..370 CDD:320325 10/21 (48%)
TM helix 7 384..409 CDD:320325 9/24 (38%)
Avpr1bNP_036054.1 7tm_4 41..>184 CDD:304433 54/142 (38%)
7tm_1 51..335 CDD:278431 95/288 (33%)
7tm_4 <126..354 CDD:304433 73/239 (31%)
DUF1856 359..408 CDD:286120 10/27 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 399..421
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG45270
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3458
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.040

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