DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCAP-R and Ptgdr

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_032988.3	Gene:	Ptgdr / 19214	MGIID:	102966	Length:	357	Species:	Mus musculus

Alignment Length:	369	Identity:	72/369 - (19%)
Similarity:	139/369 - (37%)	Gaps:	102/369 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 ILFTVIVLGNSAVLFVMF---INKNRKSRMN-----YFIKQLALADLCVGLLNVLTDIIWRITIS 188
            :||...:|||...|.::.   :...|...::     :::       |..||  .:||::.:..||
Mouse    24 VLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYV-------LVCGL--TVTDLLGKCLIS 79

  Fly   189 -----------------WRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWK 236
                             ..:||..|:...|.......:||..|:||:::.:.::.||..:.
Mouse    80 PMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQ---- 140

  Fly   237 RARHL----------VAGAWLISALFSLPILVLYEEKLIQGHPQCWIELG--------SPIAWQV 283
              ||:          |..|:.: |..:||....  .|.:|..|..|..:.        |.|.:.|
Mouse   141 --RHVTLRRGVLVAPVVAAFCL-AFCALPFAGF--GKFVQYCPGTWCFIQMIHKERSFSVIGFSV 200

  Fly   284 -YMSLVSATLFAIPALIISACYAIIVKTIWAKGSIF------------VPTERAGFGAAPARRAS 335
             |.||:        ||::   .|.:|..:.|..:::            ...:||..| :..|..|
Mouse   201 LYSSLM--------ALLV---LATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSG-SDYRHGS 253

  Fly   336 SRGIIPRAKVKTVKMTLTIVFVFIICWSPYI---IFDLLQVFGQIPHSQTNIAIATFIQSLAPLN 397
               :.|..::....:...:..:|.:|..|.|   .:...::..:......::....|:..:
Mouse   254 ---LHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVI---- 311

  Fly   398 SAANPLIYCLFSSQVFRTLSRFPPFKWFT--CCCKSYRNNSQQN 439
            |..:|.|:.:|.:.|||.|..    |.||  ...:::.::|||:
Mouse   312 SIVDPWIFIIFRTSVFRMLFH----KVFTRPLIYRNWSSHSQQS 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	65/342 (19%)
		TM helix 1	126..150	CDD:320325	6/20 (30%)
		TM helix 2	159..182	CDD:320325	5/27 (19%)
		TM helix 3	197..219	CDD:320325	6/21 (29%)
		TM helix 4	240..256	CDD:320325	5/25 (20%)
		TM helix 5	282..305	CDD:320325	6/23 (26%)
		TM helix 6	348..370	CDD:320325	4/24 (17%)
		TM helix 7	384..409	CDD:320325	4/24 (17%)
Ptgdr	NP_032988.3	7tm_1	58..318	CDD:278431	53/296 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000