DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCAP-R and srv-24

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_500957.1	Gene:	srv-24 / 190646	WormBaseID:	WBGene00005735	Length:	328	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	65/366 - (17%)
Similarity:	132/366 - (36%)	Gaps:	117/366 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALAD--------LCV 172
            :|.||........:.:::|       ..:|.:..::::..:.....:.|..:.|        |..
Worm     1 MNVFYIMSAASLPLYFMVF-------GCLLRLRCVSRSYNTTFYSILLQHCIVDIIAMTFSILNT 58

  Fly   173 GLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYV--------LVAMSIDRYDAITHP- 228
            ||.|:|  :|.:...:::...||         ..:|:|.|.        ::.:|:.||..||.|
Worm    59 GLRNIL--VIRQFMFNYQDYYLA---------AASYNSVYYFLYIRCTGIIFLSLQRYLIITAPT 112

  Fly   229 ------MNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLIQGHPQCWIELGSPIAWQVYMSL 287
                  :.|:..::    :::..|.:..|.||.:|.....|                    |.||
Worm   113 SMLTQKVQFASKFQ----IISIYWGVPTLISLVVLKDTNFK--------------------YDSL 153

  Fly   288 VSATLFA---------IPALIISACYAIIVKTIWAKGSIFVPTERAGFGAAPARRASSRGIIPRA 343
            .|.::.|         :.|||:.:...|:....:.....::....||              :.|:
Worm   154 ESMSIIAEQEVIKRNTLMALIVVSLTCILCSLAYGALFYYIRKHTAG--------------LSRS 204

  Fly   344 KVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQT-NIAIATFIQSLAP----LNSAANPL 403
            ..:.|.:... |||.::.:...:::...|.:    .||| |.....::::|.|    |.|..||
Worm   205 LRREVHLAFQ-VFVLLLAFFVILVYYAFQNY----FSQTHNTGPIFYMRALYPVANGLLSYINP- 263

  Fly   404 IYCL------FSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQ 438
             :|:      .:.||.|:::           |..|:.:..|
Worm   264 -FCILFLNKDLARQVIRSMT-----------CHKYKVSEAQ 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	59/334 (18%)
		TM helix 1	126..150	CDD:320325	2/23 (9%)
		TM helix 2	159..182	CDD:320325	7/30 (23%)
		TM helix 3	197..219	CDD:320325	3/29 (10%)
		TM helix 4	240..256	CDD:320325	4/15 (27%)
		TM helix 5	282..305	CDD:320325	8/31 (26%)
		TM helix 6	348..370	CDD:320325	4/21 (19%)
		TM helix 7	384..409	CDD:320325	7/34 (21%)
srv-24	NP_500957.1	7TM_GPCR_Srv	4..283	CDD:370977	61/352 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24224
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100